Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Filtered Gene Value Type Rank Network Comparison Type network_comparison green Interaction Map red
Results: HTML CSV LaTeX Showing element 1 to 50 of 38536 in total
Network Comparison Type  : Divided
description
Filtered
Value Type
Rank
network_comparison
green
Interaction Map
red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 0 Measured 37 2.79409 934.348 High confidence 334.401
131 1.31954 851.77 Low confidence 645.504
Ranked 242 1.09822 13895.8 High confidence 15260.6
629 1.02915 13590.3 Low confidence 13205.3
Squared 37 10.2338 1034.13 High confidence 101.05
146 1.63527 1268.51 Low confidence 775.72
Rooted 53 1.5213 18.0183 High confidence 11.844
537 1.04801 17.0804 Low confidence 16.298
1 Measured 60 1.6231 2765.82 High confidence 4489.19
4914 1.00597 7900.54 Low confidence 7853.62
Ranked 18 1.32082 245.247 High confidence 185.678
4130 1.01062 201.5 Low confidence 199.383
Squared 245 1.31131 6768.05 High confidence 8875.01
1119 1.04654 41688.5 Low confidence 43628.5
Rooted 64 1.35128 47.2654 High confidence 63.8686
4914 1.00944 72.6287 Low confidence 71.9496
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943] Measured 509 1.14278 8630.06 High confidence 7551.8
885 1.03993 8585.64 Low confidence 8255.95
Ranked 1038 1.03148 181.041 High confidence 186.741
1328 1.02218 194.038 Low confidence 198.342
Squared 295 1.27733 39351.7 High confidence 30807.7
4562 1.01928 45736 Low confidence 46617.7
Rooted 805 1.0645 79.1513 High confidence 74.3557
1092 1.0386 76.3375 Low confidence 73.5001
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120] Measured 508 1.14293 8636.87 High confidence 7556.75
880 1.04001 8587.03 Low confidence 8256.68
Ranked 1032 1.03162 180.943 High confidence 186.664
1322 1.0222 194.014 Low confidence 198.322
Squared 294 1.2776 39383.9 High confidence 30826.5
4569 1.01914 45740.5 Low confidence 46616.1
Rooted 804 1.0646 79.1931 High confidence 74.3877
1084 1.03863 76.3467 Low confidence 73.5068
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5] Measured 237 1.06457 9081.29 8530.51
514 1.1411 8532.02 High confidence 7477
Ranked 588 1.03039 185.859 Low confidence 191.507
1048 1.031 182.308 High confidence 187.96
Squared 311 1.27154 38866.5 30566.4
4138 1.02676 47372.8 Low confidence 46138.2
Rooted 378 1.04871 79.5804 75.8843
822 1.06393 78.5795 High confidence 73.8577
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7] Measured 252 1.06194 9018.94 Low confidence 8492.92
513 1.14143 8543.66 High confidence 7485.08
Ranked 637 1.029 186.751 Low confidence 192.166
1043 1.03128 182.137 High confidence 187.834
Squared 308 1.27205 38919.9 30596.2
4418 1.02256 47088.3 Low confidence 46049.4
Rooted 427 1.04731 79.1997 75.6219
811 1.06415 78.6514 High confidence 73.9102
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592] Measured 2035 1.03199 8323.04 Low confidence 8065.05
Ranked 3423 1.01523 196.707 199.702

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/