Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Value Type Interaction Map Gene Network Comparison Type red green Filtered network_comparison
Results: HTML CSV LaTeX Showing element 1 to 50 of 19268 in total
Value Type  : Ranked
description
Rank
Interaction Map
Network Comparison Type
red
green
Filtered
network_comparison
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] 18 High confidence Divided 185.678 245.247 1 1.32082
54 Subtracted 59.569
172 15260.6 13895.8 0 1364.8
242 Divided 1.09822
600 Low confidence Subtracted 13205.3 13590.3 385
629 Divided 1.02915
4130 199.383 201.5 1 1.01062
4141 Subtracted 2.117
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943] 1038 High confidence Divided 186.741 181.041 1.03148
1120 Subtracted 5.7
1328 Low confidence Divided 198.342 194.038 1.02218
1408 Subtracted 4.304
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120] 1032 High confidence Divided 186.664 180.943 1.03162
1115 Subtracted 5.721
1322 Low confidence Divided 198.322 194.014 1.0222
1406 Subtracted 4.308
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5] 588 Divided 191.507 185.859 1.03039
664 Subtracted 5.648
1048 High confidence Divided 187.96 182.308 1.031
1128 Subtracted 5.652
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7] 637 Low confidence Divided 192.166 186.751 1.029
737 Subtracted 5.415
1043 High confidence Divided 187.834 182.137 1.03128
1121 Subtracted 5.697
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592] 3423 Low confidence Divided 199.702 196.707 1.01523
3432 Subtracted 2.995
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147] 3126 High confidence Divided 0.00001 0.00001 1
Subtracted 0 0 0
3567 Low confidence 202.517 199.628 2.889
3585 Divided 1.01447
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984] 1933 High confidence Subtracted 211.633 213.703 2.07
1963 Divided 1.00978
2659 Low confidence 200.053 196.574 1.0177
2668 Subtracted 3.479
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891] 1795 203.414 199.455 3.959
1873 Divided 1.01985
2922 High confidence 0.00001 0.00001 1
Subtracted 0 0 0
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704] 4255 Low confidence Divided 202.306 200.395 1.00954
4263 Subtracted 1.911
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946] 2076 Divided 198.587 194.83 1.01928
2165 Subtracted 3.757
2421 High confidence 220.681 221.425 0.744
2439 Divided 1.00337
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655] 2864 Low confidence 200.418 197.043 1.01713
2895 Subtracted 3.375
3088 High confidence Divided 0.00001 0.00001 1
Subtracted 0 0 0
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312] 2108 Low confidence Divided 198.65 194.902 1.01923
2185 Subtracted 3.748

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/