MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	description	Network Comparison Type	Rank	Value Type	Filtered	Interaction Map	red	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 19268 in total

Value Type  : Ranked

description	Network Comparison Type	Rank	Filtered	Interaction Map	red	network_comparison	green
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	Divided	18	1	High confidence	185.678	1.32082	245.247
		242	0		15260.6	1.09822	13895.8
		629		Low confidence	13205.3	1.02915	13590.3
		4130	1		199.383	1.01062	201.5
	Subtracted	54		High confidence	185.678	59.569	245.247
		172	0		15260.6	1364.8	13895.8
		600		Low confidence	13205.3	385	13590.3
		4141	1		199.383	2.117	201.5
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	Divided	1038		High confidence	186.741	1.03148	181.041
		1328		Low confidence	198.342	1.02218	194.038
	Subtracted	1120		High confidence	186.741	5.7	181.041
		1408		Low confidence	198.342	4.304	194.038
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	Divided	1032		High confidence	186.664	1.03162	180.943
		1322		Low confidence	198.322	1.0222	194.014
	Subtracted	1115		High confidence	186.664	5.721	180.943
		1406		Low confidence	198.322	4.308	194.014
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	Divided	588			191.507	1.03039	185.859
		1048		High confidence	187.96	1.031	182.308
	Subtracted	664		Low confidence	191.507	5.648	185.859
		1128		High confidence	187.96	5.652	182.308
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	Divided	637		Low confidence	192.166	1.029	186.751
		1043		High confidence	187.834	1.03128	182.137
	Subtracted	737		Low confidence	192.166	5.415	186.751
		1121		High confidence	187.834	5.697	182.137
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	Divided	3423		Low confidence	199.702	1.01523	196.707
	Subtracted	3432				2.995
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	Divided	3126		High confidence	0.00001	1	0.00001
		3585		Low confidence	202.517	1.01447	199.628
	Subtracted	3126		High confidence	0	0	0
		3567		Low confidence	202.517	2.889	199.628
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	Divided	1963		High confidence	211.633	1.00978	213.703
		2659		Low confidence	200.053	1.0177	196.574
	Subtracted	1933		High confidence	211.633	2.07	213.703
		2668		Low confidence	200.053	3.479	196.574
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	Divided	1873			203.414	1.01985	199.455
		2922		High confidence	0.00001	1	0.00001
	Subtracted	1795		Low confidence	203.414	3.959	199.455
		2922		High confidence	0	0	0
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704]	Divided	4255		Low confidence	202.306	1.00954	200.395
	Subtracted	4263				1.911
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	Divided	2076			198.587	1.01928	194.83
		2439		High confidence	220.681	1.00337	221.425
	Subtracted	2165		Low confidence	198.587	3.757	194.83
		2421		High confidence	220.681	0.744	221.425
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	Divided	2864		Low confidence	200.418	1.01713	197.043
		3088		High confidence	0.00001	1	0.00001
	Subtracted	2895		Low confidence	200.418	3.375	197.043
		3088		High confidence	0	0	0
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	Divided	2108		Low confidence	198.65	1.01923	194.902
		2396		High confidence	220.683	1.00375	221.51

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.