MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered	network_comparison	description	Value Type	Interaction Map	green	red	Network Comparison Type	Gene	Rank

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0
network_comparison  : 0
Network Comparison Type  : Subtracted

description	Value Type	Interaction Map	green	red	Rank
3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	Squared	High confidence	17901.1	17901.1	493
		Low confidence			836
brca1 associated protein. [refseq;acc:nm_006768]	Measured	High confidence	0	0	502
	Ranked
	Squared
	Rooted
cobw-like protein. [refseq;acc:nm_018491]	Measured	Low confidence			839
	Ranked
	Squared
	Rooted
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920]	Measured				838
	Ranked
	Squared
	Rooted
gamma-glutamyltransferase. [sptrembl;acc:q14390]	Measured				841
	Ranked
	Squared
	Rooted
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440]	Measured				842
	Ranked
	Squared
	Rooted
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268]	Measured				837
	Ranked
	Squared
	Rooted
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269]	Measured				843
	Ranked
	Squared
	Rooted
h2a histone family, member j isoform 1. [refseq;acc:nm_018267]	Measured	High confidence			501
	Squared
	Rooted
histone h2a.a (h2a/a) (h2a.2). [swissprot;acc:p28001]	Measured				495
	Squared
	Rooted
histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [swissprot;acc:p02261]	Measured				494
	Squared
	Rooted
histone h2a; h2a histone family, member r. [refseq;acc:nm_170745]	Measured				497
	Squared
	Rooted
homogentisate 1,2-dioxygenase (ec 1.13.11.5) (homogentisicase) (homogentisate oxygenase) (homogentisic acid oxidase). [swissprot;acc:q93099]	Measured				499
	Ranked				501
	Squared				499
	Rooted
huntingtin interacting protein e; huntingtin interactor protein e. [refseq;acc:nm_007076]	Ranked		394	394	500
		Low confidence			840
mitochondrial 28s ribosomal protein s6 (mrp-s6). [swissprot;acc:p82932]	Measured	High confidence	0	0	496
	Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.