Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Filtered description Gene Value Type Rank Network Comparison Type green network_comparison Interaction Map red
Results: HTML CSV LaTeX Showing element 1 to 50 of 77072 in total
Filtered  : 0
description
Value Type
Rank
Network Comparison Type
green
network_comparison
Interaction Map
red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] Measured 37 Divided 934.348 2.79409 High confidence 334.401
45 Subtracted 599.947
131 Divided 851.77 1.31954 Low confidence 645.504
273 Subtracted 206.266
Ranked 172 13895.8 1364.8 High confidence 15260.6
242 Divided 1.09822
600 Subtracted 13590.3 385 Low confidence 13205.3
629 Divided 1.02915
Squared 37 1034.13 10.2338 High confidence 101.05
131 Subtracted 933.08
146 Divided 1268.51 1.63527 Low confidence 775.72
319 Subtracted 492.79
Rooted 53 Divided 18.0183 1.5213 High confidence 11.844
69 Subtracted 6.1743
537 Divided 17.0804 1.04801 Low confidence 16.298
634 Subtracted 0.7824
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829] Measured 627 4869.42 43.53 4825.89
778 Divided 1.00902
Ranked 627 10050.9 1.02953 10347.7
641 Subtracted 296.8
Squared 536 40451 180.2 40270.8
815 Divided 1.00447
Rooted 726 Subtracted 39.5126 0.4144 39.0982
768 Divided 1.0106
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528] Measured 19 26.1599 11.6763 High confidence 305.45
115 Subtracted 279.29
171 Divided 181.734 1.22585 Low confidence 222.779
635 Subtracted 41.045
Ranked 28 18499.2 5557.5 High confidence 12941.7
47 Divided 1.42943
220 Subtracted 14695.2 1162.1 Low confidence 13533.1
384 Divided 1.08587
Squared 26 0.344399 128.828 High confidence 44.3683
336 Subtracted 44.0239
697 Divided 296.481 1.03806 Low confidence 307.765
749 Subtracted 11.284
Rooted 26 Divided 3.80565 3.62106 High confidence 13.7805
28 Subtracted 9.97485
131 Divided 9.42485 1.20585 Low confidence 11.365
376 Subtracted 1.94015
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832] Measured 380 2642.79 40.82 High confidence 2683.61
451 Divided 1.01545
762 Subtracted 1609.88 16.2 Low confidence 1593.68
771 Divided 1.01017
Ranked 378 Subtracted 10806 422.4 High confidence 11228.4
379 Divided 1.03909
822 Subtracted 11854.2 21.4 Low confidence 11832.8
825 Divided 1.00181
Squared 104 Subtracted 7355.46 1264.81 High confidence 8620.27
316 Divided 1.17196

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/