MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	description	Value Type	Filtered	green	Gene	network_comparison	Network Comparison Type	red	Interaction Map

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Rank	description	Value Type	Filtered	green	network_comparison	Network Comparison Type	red	Interaction Map
1	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	Ranked	0	15915	3.70633	Divided	4294	High confidence
	ba508n22.1 (hspc025) (fragment). [sptrembl;acc:q9hcw5]	Measured		6410	6325	Subtracted	85
								Low confidence
		Rooted		60.0707	50.8706		9.20014	High confidence
								Low confidence
	cab2. [refseq;acc:nm_033419]	Squared		7.16592	716592	Divided	0.00001	High confidence
	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	Measured	1	32028.5	8870.5	Subtracted	40899	Low confidence
		Ranked		32	2	Divided	16
		Squared		242799	153113	Subtracted	395912
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked		322	107		215	High confidence
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	Squared	0	1.87479	187479	Divided	0.00001	Low confidence
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Measured	1	543.5	4.4149		2399.5
		Ranked		330	107	Subtracted	223
		Squared		69.9153	19.4914	Divided	1362.75
		Rooted		23.3131	2.10117		48.9847
					25.6716	Subtracted
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Measured		33356.5	8126		41482.5	High confidence
	mitochondrial 28s ribosomal protein s32 (s32mt) (mrp-s32) (ptd007) (hspc204). [swissprot;acc:q9y6g3]		0	0.00001	36400000	Divided	364
								Low confidence
		Ranked		21883	12977	Subtracted	8906	High confidence
								Low confidence
		Rooted		0.00001	1907880	Divided	19.0788	High confidence
								Low confidence
	mln 64 protein (star-related lipid transfer protein 3) (stard3) (start domain-containing protein 3) (cab1 protein). [swissprot;acc:q14849]	Ranked		14977	2.55362		5865
	nuclear dna-binding protein; small unique nuclear receptor corepressor; c1d dna-binding protein. [refseq;acc:nm_006333]	Squared		160184	72283	Subtracted	232467	High confidence
								Low confidence
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Ranked	1	24	2.4	Divided	10	High confidence
		Squared		322755	145743	Subtracted	468498
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Measured		2394.5	5.31521	Divided	450.5
		Squared		1357.07	28.2513		48.0356
		Rooted		48.9336	2.30547		21.225
					27.7086	Subtracted
2	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Measured		28492	7307		21185	Low confidence
	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	Ranked	0	15915	11621		4294	High confidence
	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	Squared	1	475119	141563		333556	Low confidence
	cab2. [refseq;acc:nm_033419]	Measured	0	174	17400000	Divided	0.00001	High confidence
	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]		1	543.5	4.4149		2399.5	Low confidence
		Ranked		330	107	Subtracted	223
		Squared		69.9153	19.4914	Divided	1362.75
		Rooted		23.3131	2.10117		48.9847
					25.6716	Subtracted
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Measured		33356.5	8126		41482.5	High confidence
	hbs1-like. [refseq;acc:nm_006620]	Ranked		322	107		215
	histone h4. [swissprot;acc:p02304]	Squared	0	345123	71500		273623
	homeobox protein hox-c4 (hox-3e) (cp19). [swissprot;acc:p09017]	Measured		89	8900000	Divided	0.00001	Low confidence
		Rooted		9.43398	943398
	homeobox protein hox-c6 (hox-3c) (hho.c8) (cp25). [swissprot;acc:p09630]	Squared		1.87479	187479
	lipopolysaccharide-responsive and beige-like anchor protein (cdc4-like protein) (beige-like protein). [swissprot;acc:p50851]	Measured		6410	6325	Subtracted	85	High confidence
		Rooted		60.0707	50.8706		9.20014
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Ranked	1	330	1.47982	Divided	223	Low confidence

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.