Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene description Network Comparison Type Rank Value Type Filtered Interaction Map red network_comparison green
Results: HTML CSV LaTeX Showing element 1 to 50 of 16578 in total
Value Type  : Ranked
Filtered  : 1
description
Network Comparison Type
Rank
Interaction Map
red
network_comparison
green
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446] Divided 18 High confidence 185.678 1.32082 245.247
4130 Low confidence 199.383 1.01062 201.5
Subtracted 54 High confidence 185.678 59.569 245.247
4141 Low confidence 199.383 2.117 201.5
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943] Divided 1038 High confidence 186.741 1.03148 181.041
1328 Low confidence 198.342 1.02218 194.038
Subtracted 1120 High confidence 186.741 5.7 181.041
1408 Low confidence 198.342 4.304 194.038
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120] Divided 1032 High confidence 186.664 1.03162 180.943
1322 Low confidence 198.322 1.0222 194.014
Subtracted 1115 High confidence 186.664 5.721 180.943
1406 Low confidence 198.322 4.308 194.014
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5] Divided 588 191.507 1.03039 185.859
1048 High confidence 187.96 1.031 182.308
Subtracted 664 Low confidence 191.507 5.648 185.859
1128 High confidence 187.96 5.652 182.308
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7] Divided 637 Low confidence 192.166 1.029 186.751
1043 High confidence 187.834 1.03128 182.137
Subtracted 737 Low confidence 192.166 5.415 186.751
1121 High confidence 187.834 5.697 182.137
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592] Divided 3423 Low confidence 199.702 1.01523 196.707
Subtracted 3432 2.995
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147] Divided 3126 High confidence 0.00001 1 0.00001
3585 Low confidence 202.517 1.01447 199.628
Subtracted 3126 High confidence 0 0 0
3567 Low confidence 202.517 2.889 199.628
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984] Divided 1963 High confidence 211.633 1.00978 213.703
2659 Low confidence 200.053 1.0177 196.574
Subtracted 1933 High confidence 211.633 2.07 213.703
2668 Low confidence 200.053 3.479 196.574
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891] Divided 1873 203.414 1.01985 199.455
2922 High confidence 0.00001 1 0.00001
Subtracted 1795 Low confidence 203.414 3.959 199.455
2922 High confidence 0 0 0
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704] Divided 4255 Low confidence 202.306 1.00954 200.395
Subtracted 4263 1.911
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946] Divided 2076 198.587 1.01928 194.83
2439 High confidence 220.681 1.00337 221.425
Subtracted 2165 Low confidence 198.587 3.757 194.83
2421 High confidence 220.681 0.744 221.425
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655] Divided 2864 Low confidence 200.418 1.01713 197.043
3088 High confidence 0.00001 1 0.00001
Subtracted 2895 Low confidence 200.418 3.375 197.043
3088 High confidence 0 0 0
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312] Divided 2108 Low confidence 198.65 1.01923 194.902
2396 High confidence 220.683 1.00375 221.51
Subtracted 2185 Low confidence 198.65 3.748 194.902
2391 High confidence 220.683 0.827 221.51
14.5 kda translational inhibitor protein (p14.5) (uk114 antigen homolog). [swissprot;acc:p52758] Divided 1044 Low confidence 201.723 1.02415 196.966
2366 High confidence 203.353 1.00407 202.529

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/