MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Gene	description	Rank	green	red	Value Type	Network Comparison Type	network_comparison	Interaction Map

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0

description	Rank	green	red	Value Type	Network Comparison Type	network_comparison	Interaction Map
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	37	934.348	334.401	Measured	Divided	2.79409	High confidence
		1034.13	101.05	Squared		10.2338
	45	934.348	334.401	Measured	Subtracted	599.947
	53	18.0183	11.844	Rooted	Divided	1.5213
	69				Subtracted	6.1743
	131	851.77	645.504	Measured	Divided	1.31954	Low confidence
		1034.13	101.05	Squared	Subtracted	933.08	High confidence
	146	1268.51	775.72		Divided	1.63527	Low confidence
	172	13895.8	15260.6	Ranked	Subtracted	1364.8	High confidence
	242				Divided	1.09822
	273	851.77	645.504	Measured	Subtracted	206.266	Low confidence
	319	1268.51	775.72	Squared		492.79
	537	17.0804	16.298	Rooted	Divided	1.04801
	600	13590.3	13205.3	Ranked	Subtracted	385
	629				Divided	1.02915
	634	17.0804	16.298	Rooted	Subtracted	0.7824
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829]	536	40451	40270.8	Squared		180.2
	627	4869.42	4825.89	Measured		43.53
		10050.9	10347.7	Ranked	Divided	1.02953
	641				Subtracted	296.8
	726	39.5126	39.0982	Rooted		0.4144
	768				Divided	1.0106
	778	4869.42	4825.89	Measured		1.00902
	815	40451	40270.8	Squared		1.00447
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	19	26.1599	305.45	Measured		11.6763	High confidence
	26	0.344399	44.3683	Squared		128.828
		3.80565	13.7805	Rooted		3.62106
	28				Subtracted	9.97485
		18499.2	12941.7	Ranked		5557.5
	47				Divided	1.42943
	115	26.1599	305.45	Measured	Subtracted	279.29
	131	9.42485	11.365	Rooted	Divided	1.20585	Low confidence
	171	181.734	222.779	Measured		1.22585
	220	14695.2	13533.1	Ranked	Subtracted	1162.1
	336	0.344399	44.3683	Squared		44.0239	High confidence
	376	9.42485	11.365	Rooted		1.94015	Low confidence
	384	14695.2	13533.1	Ranked	Divided	1.08587
	635	181.734	222.779	Measured	Subtracted	41.045
	697	296.481	307.765	Squared	Divided	1.03806
	749				Subtracted	11.284
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	104	7355.46	8620.27			1264.81	High confidence
	316				Divided	1.17196
	335	32.0298	30.7424	Rooted	Subtracted	1.2874
	370				Divided	1.04188
	378	10806	11228.4	Ranked	Subtracted	422.4
	379				Divided	1.03909
	380	2642.79	2683.61	Measured	Subtracted	40.82
	451				Divided	1.01545
	584	6490.54	6603.33	Squared	Subtracted	112.79	Low confidence
	762	1609.88	1593.68	Measured		16.2

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.