MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Filtered	Gene	Value Type	description	Rank	Network Comparison Type	network_comparison	Interaction Map	green	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 77072 in total

Filtered  : 0
Value Type  : Measured

description	Rank	Network Comparison Type	network_comparison	Interaction Map	green	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	37	Divided	2.79409	High confidence	934.348	334.401
	45	Subtracted	599.947
	131	Divided	1.31954	Low confidence	851.77	645.504
	273	Subtracted	206.266
17-beta-hydroxysteroid dehydrogenase type vii-like. [refseq;acc:nm_182829]	627		43.53		4869.42	4825.89
	778	Divided	1.00902
25-hydroxyvitamin d-1 alpha hydroxylase, mitochondrial precursor (ec 1.14.-.-) (25-ohd-1 alpha-hydroxylase) (25-hydroxyvitamin d3 1- alpha-hydroxylase) (vd3 1a hydroxylase) (p450c1 alpha) (p450vd1- alpha). [swissprot;acc:o15528]	19		11.6763	High confidence	26.1599	305.45
	115	Subtracted	279.29
	171	Divided	1.22585	Low confidence	181.734	222.779
	635	Subtracted	41.045
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	380		40.82	High confidence	2642.79	2683.61
	451	Divided	1.01545
	762	Subtracted	16.2	Low confidence	1609.88	1593.68
	771	Divided	1.01017
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	434	Subtracted	17.27	High confidence	2263.85	2281.12
	474	Divided	1.00763
	750	Subtracted	18.59	Low confidence	2331.31	2349.9
	785	Divided	1.00797
3 beta-hydroxysteroid dehydrogenase (fragments). [sptrembl;acc:q9udk8]	457	Subtracted	8	High confidence	5046.33	5038.33
	492	Divided	1.00159
	793	Subtracted	8	Low confidence
	822	Divided	1.00159
3-hydroxyisobutyryl-coenzyme a hydrolase. [refseq;acc:nm_014362]	321	Subtracted	71.92	High confidence	2853.65	2925.57
	438	Divided	1.0252
	473	Subtracted	82.7	Low confidence	1932.95	2015.65
	581	Divided	1.04278
3-ketoacyl-coa thiolase, peroxisomal precursor (ec 2.3.1.16) (beta- ketothiolase) (acetyl-coa acyltransferase) (peroxisomal 3-oxoacyl- coa thiolase). [swissprot;acc:p09110]	264	Subtracted	115.5	High confidence	1721.76	1837.26
	346	Divided	1.06708
	406	Subtracted	116.24	Low confidence	1500.63	1616.87
	459	Divided	1.07746
4-aminobutyrate aminotransferase, mitochondrial precursor (ec 2.6.1.19) (gamma-amino-n-butyrate transaminase) (gaba transaminase) (gaba aminotransferase) (gaba-at) (gaba-t). [swissprot;acc:p80404]	121		1.3721	High confidence	14.3333	19.6667
	460	Subtracted	5.3334
	789		9.81	Low confidence	3822.12	3831.93
	815	Divided	1.00257
40s ribosomal protein s10. [swissprot;acc:p46783]	513		1.05788		1135.73	1201.47
	537	Subtracted	65.74
40s ribosomal protein s12. [swissprot;acc:p25398]	575		53.51		2194.28	2140.77
	661	Divided	1.025
40s ribosomal protein s15 (rig protein). [swissprot;acc:p11174]	205	Subtracted	154.38	High confidence	1337.54	1183.16
	258	Divided	1.13048
	317	Subtracted	159.58	Low confidence	1327.26	1167.68
	346	Divided	1.13666
40s ribosomal protein s17. [swissprot;acc:p08708]	755		1.01203		146.011	147.767
	829	Subtracted	1.756
40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]	143		235.83	High confidence	1735.23	1499.4
	222	Divided	1.15728
	274	Subtracted	205.23	Low confidence	2370.67	2165.44
	414	Divided	1.09478
40s ribosomal protein s25. [swissprot;acc:p25111]	736		1.01365		1530.84	1551.74
	738	Subtracted	20.9

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.