MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Filtered	Rank	Value Type	Gene	Network Comparison Type	green	Interaction Map	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 38536 in total

Network Comparison Type  : Divided

description	Filtered	Rank	Value Type	green	Interaction Map	network_comparison	red
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	0	37	Measured	934.348	High confidence	2.79409	334.401
			Squared	1034.13		10.2338	101.05
		53	Rooted	18.0183		1.5213	11.844
		131	Measured	851.77	Low confidence	1.31954	645.504
		146	Squared	1268.51		1.63527	775.72
		242	Ranked	13895.8	High confidence	1.09822	15260.6
		537	Rooted	17.0804	Low confidence	1.04801	16.298
		629	Ranked	13590.3		1.02915	13205.3
	1	18		245.247	High confidence	1.32082	185.678
		60	Measured	2765.82		1.6231	4489.19
		64	Rooted	47.2654		1.35128	63.8686
		245	Squared	6768.05		1.31131	8875.01
		1119		41688.5	Low confidence	1.04654	43628.5
		4130	Ranked	201.5		1.01062	199.383
		4914	Measured	7900.54		1.00597	7853.62
			Rooted	72.6287		1.00944	71.9496
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]		295	Squared	39351.7	High confidence	1.27733	30807.7
		509	Measured	8630.06		1.14278	7551.8
		805	Rooted	79.1513		1.0645	74.3557
		885	Measured	8585.64	Low confidence	1.03993	8255.95
		1038	Ranked	181.041	High confidence	1.03148	186.741
		1092	Rooted	76.3375	Low confidence	1.0386	73.5001
		1328	Ranked	194.038		1.02218	198.342
		4562	Squared	45736		1.01928	46617.7
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]		294		39383.9	High confidence	1.2776	30826.5
		508	Measured	8636.87		1.14293	7556.75
		804	Rooted	79.1931		1.0646	74.3877
		880	Measured	8587.03	Low confidence	1.04001	8256.68
		1032	Ranked	180.943	High confidence	1.03162	186.664
		1084	Rooted	76.3467	Low confidence	1.03863	73.5068
		1322	Ranked	194.014		1.0222	198.322
		4569	Squared	45740.5		1.01914	46616.1
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]		237	Measured	9081.29		1.06457	8530.51
		311	Squared	38866.5	High confidence	1.27154	30566.4
		378	Rooted	79.5804	Low confidence	1.04871	75.8843
		514	Measured	8532.02	High confidence	1.1411	7477
		588	Ranked	185.859	Low confidence	1.03039	191.507
		822	Rooted	78.5795	High confidence	1.06393	73.8577
		1048	Ranked	182.308		1.031	187.96
		4138	Squared	47372.8	Low confidence	1.02676	46138.2
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]		252	Measured	9018.94		1.06194	8492.92
		308	Squared	38919.9	High confidence	1.27205	30596.2
		427	Rooted	79.1997	Low confidence	1.04731	75.6219
		513	Measured	8543.66	High confidence	1.14143	7485.08
		637	Ranked	186.751	Low confidence	1.029	192.166
		811	Rooted	78.6514	High confidence	1.06415	73.9102
		1043	Ranked	182.137		1.03128	187.834
		4418	Squared	47088.3	Low confidence	1.02256	46049.4
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]		2035	Measured	8323.04		1.03199	8065.05
		2766	Rooted	74.9741		1.03282	72.5914

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.