MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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description	Rank	Gene	network_comparison	Network Comparison Type	green	Filtered	Value Type	red	Interaction Map

Results: HTML CSV LaTeX

Showing element 1 to 50 of 19268 in total

Value Type  : Ranked

description	Rank	network_comparison	Network Comparison Type	green	Filtered	red	Interaction Map
1,4-alpha-glucan branching enzyme (ec 2.4.1.18) (glycogen branching enzyme) (brancher enzyme). [swissprot;acc:q04446]	18	1.32082	Divided	245.247	1	185.678	High confidence
	54	59.569	Subtracted
	172	1364.8		13895.8	0	15260.6
	242	1.09822	Divided
	600	385	Subtracted	13590.3		13205.3	Low confidence
	629	1.02915	Divided
	4130	1.01062		201.5	1	199.383
	4141	2.117	Subtracted
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (ec 2.3.1.51) (1- agp acyltransferase 1) (1-agpat 1) (lysophosphatidic acid acyltransferase-alpha) (lpaat-alpha) (1-acylglycerol-3-phosphate o- acyltransferase 1) (g15 protein). [swissprot;acc:q99943]	1038	1.03148	Divided	181.041		186.741	High confidence
	1120	5.7	Subtracted
	1328	1.02218	Divided	194.038		198.342	Low confidence
	1408	4.304	Subtracted
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (ec 2.3.1.51) (1- agp acyltransferase 2) (1-agpat 2) (lysophosphatidic acid acyltransferase-beta) (lpaat-beta) (1-acylglycerol-3-phosphate o- acyltransferase 2). [swissprot;acc:o15120]	1032	1.03162	Divided	180.943		186.664	High confidence
	1115	5.721	Subtracted
	1322	1.0222	Divided	194.014		198.322	Low confidence
	1406	4.308	Subtracted
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (ec 2.3.1.51) (1- agp acyltransferase 4) (1-agpat 4) (lysophosphatidic acid acyltransferase-delta) (lpaat-delta) (1-acylglycerol-3-phosphate o- acyltransferase 4). [swissprot;acc:q9nrz5]	588	1.03039	Divided	185.859		191.507
	664	5.648	Subtracted
	1048	1.031	Divided	182.308		187.96	High confidence
	1128	5.652	Subtracted
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (ec 2.3.1.51) (1- agp acyltransferase 3) (1-agpat 3) (lysophosphatidic acid acyltransferase-gamma) (lpaat-gamma) (1-acylglycerol-3-phosphate o- acyltransferase 3). [swissprot;acc:q9nrz7]	637	1.029	Divided	186.751		192.166	Low confidence
	737	5.415	Subtracted
	1043	1.03128	Divided	182.137		187.834	High confidence
	1121	5.697	Subtracted
1-aminocyclopropane-1-carboxylate synthase. [refseq;acc:nm_032592]	3423	1.01523	Divided	196.707		199.702	Low confidence
	3432	2.995	Subtracted
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 (ec 3.1.4.11) (phosphoinositide phospholipase c) (plc-beta-4) (phospholipase c-beta-4). [swissprot;acc:q15147]	3126	0		0		0	High confidence
		1	Divided	0.00001		0.00001
	3567	2.889	Subtracted	199.628		202.517	Low confidence
	3585	1.01447	Divided
10 kda heat shock protein, mitochondrial (hsp10) (10 kda chaperonin) (cpn10). [swissprot;acc:q04984]	1933	2.07	Subtracted	213.703		211.633	High confidence
	1963	1.00978	Divided
	2659	1.0177		196.574		200.053	Low confidence
	2668	3.479	Subtracted
10-formyltetrahydrofolate dehydrogenase (ec 1.5.1.6) (10-fthfdh). [swissprot;acc:o75891]	1795	3.959		199.455		203.414
	1873	1.01985	Divided
	2922	0	Subtracted	0		0	High confidence
		1	Divided	0.00001		0.00001
130 kda leucine-rich protein (lrp 130) (gp130) (leucine-rich ppr-motif containing protein). [swissprot;acc:p42704]	4255	1.00954		200.395		202.306	Low confidence
	4263	1.911	Subtracted
14-3-3 protein beta/alpha (protein kinase c inhibitor protein-1) (kcip-1) (protein 1054). [swissprot;acc:p31946]	2076	1.01928	Divided	194.83		198.587
	2165	3.757	Subtracted
	2421	0.744		221.425		220.681	High confidence
	2439	1.00337	Divided
14-3-3 protein epsilon (mitochondrial import stimulation factor l subunit) (protein kinase c inhibitor protein-1) (kcip-1) (14-3-3e). [swissprot;acc:p42655]	2864	1.01713		197.043		200.418	Low confidence
	2895	3.375	Subtracted
	3088	0		0		0	High confidence
		1	Divided	0.00001		0.00001
14-3-3 protein zeta/delta (protein kinase c inhibitor protein-1) (kcip-1) (factor activating exoenzyme s) (fas). [swissprot;acc:p29312]	2108	1.01923		194.902		198.65	Low confidence
	2185	3.748	Subtracted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.