MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Rank	description	Network Comparison Type	Value Type	Interaction Map	green	Filtered	network_comparison	red

Results: HTML CSV LaTeX

Showing element 1 to 50 of 66312 in total

Filtered  : 1

Rank	description	Network Comparison Type	Value Type	Interaction Map	green	network_comparison	red
1	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	Divided	Ranked	Low confidence	32	2	16
		Subtracted	Measured		32028.5	8870.5	40899
			Squared		242799	153113	395912
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]		Ranked	High confidence	322	107	215
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Divided	Measured	Low confidence	543.5	4.4149	2399.5
			Squared		69.9153	19.4914	1362.75
			Rooted		23.3131	2.10117	48.9847
		Subtracted	Ranked		330	107	223
			Rooted		23.3131	25.6716	48.9847
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]		Measured	High confidence	33356.5	8126	41482.5
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Divided	Ranked		24	2.4	10
		Subtracted	Squared		322755	145743	468498
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Divided	Measured		2394.5	5.31521	450.5
			Squared		1357.07	28.2513	48.0356
			Rooted		48.9336	2.30547	21.225
		Subtracted				27.7086
2	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]		Measured	Low confidence	28492	7307	21185
	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]		Squared		475119	141563	333556
	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Divided	Measured		543.5	4.4149	2399.5
			Squared		69.9153	19.4914	1362.75
			Rooted		23.3131	2.10117	48.9847
		Subtracted	Ranked		330	107	223
			Rooted		23.3131	25.6716	48.9847
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]		Measured	High confidence	33356.5	8126	41482.5
	hbs1-like. [refseq;acc:nm_006620]		Ranked		322	107	215
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Divided		Low confidence	330	1.47982	223
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]			High confidence	28	1.86667	15
		Subtracted	Squared		263351	143938	407289
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Divided	Measured		2394.5	5.31521	450.5
			Squared		1357.07	28.2513	48.0356
			Rooted		48.9336	2.30547	21.225
		Subtracted				27.7086
3	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Divided	Ranked	Low confidence	330	1.47982	223
	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]		Measured		543.5	4.4149	2399.5
			Squared		69.9153	19.4914	1362.75
			Rooted		23.3131	2.10117	48.9847
		Subtracted	Ranked		330	107	223
			Rooted		23.3131	25.6716	48.9847
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Divided	Ranked	High confidence	28	1.86667	15
		Subtracted	Squared		263351	143938	407289
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]		Measured		33356.5	8126	41482.5
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Divided			698.5	3.71868	2597.5
			Squared		115.48	13.8285	1596.92
			Rooted		26.4292	1.92839	50.9657
		Subtracted				24.5365
	mitochondrial solute carrier protein. [refseq;acc:nm_145305]		Measured	Low confidence	28492	7307	21185
	rad50-interacting protein 1. [refseq;acc:nm_021930]		Ranked	High confidence	232	105	337
	vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274]		Squared	Low confidence	475045	141539	333506
4	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]		Measured		43509.4	7035.1	36474.3
	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	Divided	Ranked		330	1.47982	223

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.