MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	Gene	description	Value Type	Network Comparison Type	red	Interaction Map	Filtered	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1 to 50 of 66312 in total

Filtered  : 1

Rank	description	Value Type	Network Comparison Type	red	Interaction Map	green	network_comparison
1	carboxypeptidase d precursor (ec 3.4.17.-) (gp180). [swissprot;acc:o75976]	Measured	Subtracted	40899	Low confidence	32028.5	8870.5
		Ranked	Divided	16		32	2
		Squared	Subtracted	395912		242799	153113
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked		215	High confidence	322	107
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]	Measured	Divided	2399.5	Low confidence	543.5	4.4149
		Ranked	Subtracted	223		330	107
		Squared	Divided	1362.75		69.9153	19.4914
		Rooted		48.9847		23.3131	2.10117
			Subtracted				25.6716
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Measured		41482.5	High confidence	33356.5	8126
	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Ranked	Divided	10		24	2.4
		Squared	Subtracted	468498		322755	145743
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Measured	Divided	450.5		2394.5	5.31521
		Squared		48.0356		1357.07	28.2513
		Rooted		21.225		48.9336	2.30547
			Subtracted				27.7086
2	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	Measured		21185	Low confidence	28492	7307
	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	Squared		333556		475119	141563
	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Measured	Divided	2399.5		543.5	4.4149
		Ranked	Subtracted	223		330	107
		Squared	Divided	1362.75		69.9153	19.4914
		Rooted		48.9847		23.3131	2.10117
			Subtracted				25.6716
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Measured		41482.5	High confidence	33356.5	8126
	hbs1-like. [refseq;acc:nm_006620]	Ranked		215		322	107
	lysosome-associated membrane glycoprotein 1 precursor (lamp-1) (cd107a antigen). [swissprot;acc:p11279]		Divided	223	Low confidence	330	1.47982
	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]			15	High confidence	28	1.86667
		Squared	Subtracted	407289		263351	143938
	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Measured	Divided	450.5		2394.5	5.31521
		Squared		48.0356		1357.07	28.2513
		Rooted		21.225		48.9336	2.30547
			Subtracted				27.7086
3	cell division protein kinase 4 (ec 2.7.1.37) (cyclin-dependent kinase 4) (psk-j3). [swissprot;acc:p11802]	Ranked	Divided	223	Low confidence	330	1.47982
	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	Measured		2399.5		543.5	4.4149
		Ranked	Subtracted	223		330	107
		Squared	Divided	1362.75		69.9153	19.4914
		Rooted		48.9847		23.3131	2.10117
			Subtracted				25.6716
	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Ranked	Divided	15	High confidence	28	1.86667
		Squared	Subtracted	407289		263351	143938
	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Measured		41482.5		33356.5	8126
	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]		Divided	2597.5		698.5	3.71868
		Squared		1596.92		115.48	13.8285
		Rooted		50.9657		26.4292	1.92839
			Subtracted				24.5365
	mitochondrial solute carrier protein. [refseq;acc:nm_145305]	Measured		21185	Low confidence	28492	7307
	rad50-interacting protein 1. [refseq;acc:nm_021930]	Ranked		337	High confidence	232	105
	vitelliform macular dystrophy 2-like protein 2. [refseq;acc:nm_153274]	Squared		333506	Low confidence	475045	141539
4	bestrophin (vitelliform macular dystrophy protein) (tu15b). [swissprot;acc:o76090]	Measured		36474.3		43509.4	7035.1
	cell division protein kinase 6 (ec 2.7.1.37) (serine/threonine protein kinase plstire). [swissprot;acc:q00534]	Ranked	Divided	223		330	1.47982

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.