MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Gene	Network Comparison Type	Rank	red	description	Value Type	Interaction Map	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 1 to 50 of 25824 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	red	description	Value Type	network_comparison	green
1	10	putative glialblastoma cell differentiation-related; putative glialblastoma cell differentiation-related protein. [refseq;acc:nm_016172]	Ranked	2.4	24
	21.225	rad50-interacting protein 1. [refseq;acc:nm_021930]	Rooted	2.30547	48.9336
	48.0356		Squared	28.2513	1357.07
	450.5		Measured	5.31521	2394.5
2	15	mannosyl-oligosaccharide 1,2-alpha-mannosidase ib (ec 3.2.1.113) (processing alpha-1,2-mannosidase ib) (alpha-1,2-mannosidase ib) (mannosidase alpha class 1a member 2). [swissprot;acc:o60476]	Ranked	1.86667	28
	21.225	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Rooted	2.30547	48.9336
	48.0356		Squared	28.2513	1357.07
	450.5		Measured	5.31521	2394.5
3	15	cytohesin 1 (sec7 homolog b2-1). [swissprot;acc:q15438]	Ranked	1.86667	28
	50.9657	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Rooted	1.92839	26.4292
	1596.92		Squared	13.8285	115.48
	2597.5		Measured	3.71868	698.5
4	15	cytohesin 2 (arf nucleotide-binding site opener) (arno protein) (arf exchange factor). [swissprot;acc:q99418]	Ranked	1.86667	28
	50.9657	hbs1-like. [refseq;acc:nm_006620]	Rooted	1.92839	26.4292
	1596.92		Squared	13.8285	115.48
	2597.5		Measured	3.71868	698.5
5	15	cytohesin 4. [swissprot;acc:q9uia0]	Ranked	1.86667	28
	33.9632	junctophilin 3 (junctophilin type 3) (jp-3). [swissprot;acc:q8wxh2]	Rooted	1.84327	18.4255
	314.926		Squared	11.544	27.2805
	1153.5		Measured	3.39764	339.5
6	15	cytohesin 3 (arf nucleotide-binding site opener 3) (arno3 protein) (general receptor of phosphoinositides 1) (grp1). [swissprot;acc:o43739]	Ranked	1.86667	28
	33.9632	junctophilin 2 (junctophilin type 2) (jp-2). [swissprot;acc:q9br39]	Rooted	1.84327	18.4255
	314.926		Squared	11.544	27.2805
	1153.5		Measured	3.39764	339.5
7	33.9632	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]	Rooted	1.84327	18.4255
	215	homeobox protein hlx1 (homeobox protein hb24). [swissprot;acc:q14774]	Ranked	1.49767	322
	314.926	sphingomyelin phosphodiesterase 2 (ec 3.1.4.12) (neutral sphingomyelinase) (nsmase) (n-smase) (lyso-platelet activating factor- phospholipase c) (lyso-paf-plc). [swissprot;acc:o60906]	Squared	11.544	27.2805
	1153.5		Measured	3.39764	339.5
8	33.9632	db83 protein. [swissprot;acc:p57088]	Rooted	1.84327	18.4255
	215	hbs1-like. [refseq;acc:nm_006620]	Ranked	1.49767	322
	314.926	db83 protein. [swissprot;acc:p57088]	Squared	11.544	27.2805
	1153.5		Measured	3.39764	339.5
9	19.9625	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	Rooted	1.79326	35.798
	37.5863		Squared	10.3414	388.696
	212	xpa binding protein 1; mbd2 interactor protein; putative atp(gtp)-binding protein. [refseq;acc:nm_007266]	Ranked	1.45755	309
	398.5	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	Measured	3.21581	1281.5
10	19.9625	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	Rooted	1.79326	35.798
	37.5863		Squared	10.3414	388.696
	212	protein x 0004. [refseq;acc:nm_016301]	Ranked	1.45755	309
	398.5	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	Measured	3.21581	1281.5
11	19.9625	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]	Rooted	1.79326	35.798
	37.5863		Squared	10.3414	388.696
	337	rad50-interacting protein 1. [refseq;acc:nm_021930]	Ranked	1.45259	232
	398.5	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]	Measured	3.21581	1281.5
12	19.9625	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]	Rooted	1.79326	35.798
	37.5863		Squared	10.3414	388.696
	337	rho-related btb domain-containing protein 2 (deleted in breast cancer 2 gene protein) (p83). [swissprot;acc:q9byz6]	Ranked	1.45259	232
	398.5	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]	Measured	3.21581	1281.5
13	19.9625	cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912]	Rooted	1.79326	35.798
	37.5863		Squared	10.3414	388.696

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.