MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Value Type	Network Comparison Type	Rank	description	red	Interaction Map	Filtered	network_comparison	green

Results: HTML CSV LaTeX

Showing element 101 to 150 of 25824 in total

Value Type  : Measured
Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	red	network_comparison	green
101	cullin homolog 2 (cul-2). [swissprot;acc:q13617]	2353.63	1.3705	3225.65
102	presenilin 1 (ps-1) (s182 protein). [swissprot;acc:p49768]
103	cullin homolog 1 (cul-1). [swissprot;acc:q13616]
104	musashi 2 isoform a. [refseq;acc:nm_138962]	4241.57	1.36996	5810.79
105	musashi 1. [refseq;acc:nm_002442]
106	nuclear protein ukp68. [refseq;acc:nm_024824]
107	20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298]	4266.04	1.36977	5843.51
108	filamin b, beta (actin binding protein 278); beta filamin; filamin 1 (actin-binding protein-280)-like; filamin b, beta (actin-binding protein-278); filamin b, beta. [refseq;acc:nm_001457]	4366.44	1.35116	5899.76
109	rev1-like; rev1 protein; rev1 (yeast homolog)- like. [refseq;acc:nm_016316]
110	protein arginine n-methyltransferase 1 (ec 2.1.1.-) (interferon receptor 1-bound protein 4). [swissprot;acc:q99873]
111	protein arginine n-methyltransferase 4 (ec 2.1.1.-). [swissprot;acc:q9nr22]
112	u1 small nuclear ribonucleoprotein 70 kda (u1 snrnp 70 kda) (snrnp70) (u1-70k). [swissprot;acc:p08621]
113	filamin a (alpha-filamin) (filamin 1) (endothelial actin-binding protein) (abp-280) (nonmuscle filamin). [swissprot;acc:p21333]
114	huntingtin interacting protein c. [refseq;acc:nm_012272]	4300.47	1.35048	5807.72
115	28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	21185	1.34491	28492
116	pantothenate kinase 1 (ec 2.7.1.33) (pantothenic acid kinase 1) (hpank1) (hpank). [swissprot;acc:q8te04]
117	pantothenate kinase 2, mitochondrial precursor (ec 2.7.1.33) (pantothenic acid kinase 2) (hpank2). [swissprot;acc:q9bz23]
118	pantothenate kinase 3 (ec 2.7.1.33) (pantothenic acid kinase 3) (hpank3). [swissprot;acc:q9h999]
119	mitochondrial solute carrier protein. [refseq;acc:nm_145305]
120	high-mobility group 20b; sox-like transcriptional factor; swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily e, member 1-related. [refseq;acc:nm_006339]	5136.78	1.34247	6895.98
121	transcription factor jun-b. [swissprot;acc:p17275]	5579.18	1.3422	7488.4
122	high-mobility group 20a. [refseq;acc:nm_018200]	5140.14	1.34112	6893.53
123	cysteine endopeptidase aut-like 2 isoform a; autophagy-related cysteine endopeptidase 2; autophagin 2. [refseq;acc:nm_052936]	24260.3	1.33503	18172.1
124	microtubule-associated proteins 1a/1b light chain 3b (map1a/map1b lc3 b) (map1a/1b light chain 3 b). [swissprot;acc:q9gzq8]	24255.7	1.33501	18168.9
125	microtubule-associated proteins 1a/1b light chain 3a (map1a/map1b lc3 a) (map1a/1b light chain 3 a). [swissprot;acc:q9h492]
126	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]	24250	1.33499	18164.9
127	transcription factor jun-d. [swissprot;acc:p17535]	5638.2	1.33436	7523.39
128	luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	4355.61	1.3341	5810.82
129	luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	4358.13	1.33348	5811.49
130	forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	2234.68	1.33287	2978.53
131	forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]	2234.73	1.33285	2978.57
132	forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	2236.61	1.33253	2980.35
133	gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278]	23421.5	1.33225	17580.4
134	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	21785.2	1.32626	16426.1
135	apg3p; pc3-96 protein. [refseq;acc:nm_022488]
136	nuclear transcription factor y subunit gamma (nf-y protein chain c) (nuclear factor yc) (nf-yc) (ccaat-binding transcription factor subunit c) (cbf-c) (transactivator hsm-1/2). [swissprot;acc:q13952]	3620.77	1.31556	4763.34
137	ccaat-binding transcription factor subunit b (cbf-b) (nf-y protein chain a) (nf-ya) (caat-box dna binding protein subunit a). [swissprot;acc:p23511]
138	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	2755.15	1.31555	2094.3
139	potassium channel-interacting protein 4 isoform 4; calsenilin-like protein. [refseq;acc:nm_147183]	2759.61	1.31442	2099.49
140	kv channel interacting protein 2 isoform 4; a-type potassium channel modulatory protein 2; cardiac voltage gated potassium channel modulatory subunit. [refseq;acc:nm_173193]	2760.28	1.31425	2100.27
141	small nuclear ribonucleoprotein sm d2 (snrnp core protein d2) (sm-d2). [swissprot;acc:p43330]	4405.4	1.3125	5782.08
142	metalloprotease 1; metalloprotease 1 (pitrilysin family). [refseq;acc:nm_014889]	9276.47	1.30832	7090.37
143	beta-1,4 mannosyltransferase. [refseq;acc:nm_019109]	9275.1	1.30826	7089.65
144	sad1/unc-84 protein-like 1. [swissprot;acc:o94901]	3349.9	1.30231	4362.61
145	ubiquitin activating enzyme e1-like protein. [refseq;acc:nm_006395]	16771.5	1.30122	12889.1
146	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]	11068	1.30082	8508.5
147	putative breast adenocarcinoma marker (32kd). [refseq;acc:nm_014453]
148	associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463]
149	neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079]
150	protein hspc134 (protein cda04). [swissprot;acc:q9by43]

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.