MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

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Gene	Network Comparison Type	Rank	description	Value Type	Interaction Map	Filtered	green	network_comparison	red

Results: HTML CSV LaTeX

Showing element 501 to 550 of 25824 in total

Network Comparison Type  : Divided
Interaction Map  : High confidence
Filtered  : 1

Rank	description	Value Type	green	network_comparison	red
126	associated molecule with the sh3 domain of stam (amsh) like protein. [refseq;acc:nm_020799]	Ranked	114	1.21277	94
	cysteine endopeptidase aut-like isoform b. [refseq;acc:nm_178326]	Measured	18164.9	1.33499	24250
	high-mobility group 20b; sox-like transcriptional factor; swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily e, member 1-related. [refseq;acc:nm_006339]	Rooted	75.1387	1.23311	60.9342
	serine/threonine protein phosphatase pp1-alpha 1 catalytic subunit (ec 3.1.3.16) (pp-1a). [swissprot;acc:p08129]	Squared	124480	1.52616	189976
127	cyclin-dependent kinases regulatory subunit 1 (cks-1) (sid1334) (pnas-16 / pnas-143). [swissprot;acc:p33551]		58423.3	1.51365	88432.6
	high-mobility group 20a. [refseq;acc:nm_018200]	Rooted	75.094	1.23236	60.9353
	putative breast adenocarcinoma marker (32kd). [refseq;acc:nm_014453]	Ranked	114	1.21277	94
	transcription factor jun-d. [swissprot;acc:p17535]	Measured	7523.39	1.33436	5638.2
128	associated molecule with the sh3 domain of stam. [refseq;acc:nm_006463]	Ranked	114	1.21277	94
	luc7-like 2; cgi-74 protein; cgi-59 protein. [refseq;acc:nm_016019]	Measured	5810.82	1.3341	4355.61
	pnas-18. [sptrembl;acc:q9bzu3]	Squared	58155.8	1.50952	87787.3
	tar dna-binding protein-43 (tdp-43). [swissprot;acc:q13148]	Rooted	39.0445	1.23069	48.0515
129	dj820b18.1 (similar to nuclear cap binding protein) (fragment). [sptrembl;acc:q8wwk2]		66.7323	1.23044	54.2343
	luc7-like; sarcoplasmic reticulum protein luc7b1. [refseq;acc:nm_018032]	Measured	5811.49	1.33348	4358.13
	neuroendocrine differentiation factor; comparative gene identification transcript 149. [refseq;acc:nm_016079]	Ranked	114	1.21277	94
	pre-mrna cleavage complex ii protein pcf11 (fragment). [swissprot;acc:o94913]	Squared	118639	1.50257	178263
130	44050 protein. [refseq;acc:nm_178832]		99628.4	1.4861	148058
	forkhead box p4; fork head-related protein like a; winged-helix repressor foxp4. [refseq;acc:nm_138457]	Measured	2978.53	1.33287	2234.68
	formin binding protein 3; fas-ligand associated factor 1; huntingtin-interacting protein a; ny-ren-6 antigen. [refseq;acc:nm_017892]	Rooted	67.5701	1.22626	55.1026
	protein hspc134 (protein cda04). [swissprot;acc:q9by43]	Ranked	114	1.21277	94
131	forkhead box protein p1 (hspc215). [swissprot;acc:q9h334]	Measured	2978.57	1.33285	2234.73
	huntingtin-interacting protein hypa/fbp11 (fragment). [sptrembl;acc:o75404]	Rooted	67.5537	1.22577	55.1113
	nuclear inhibitor of protein phosphatase-1 (nipp-1) (protein phosphatase 1, regulatory inhibitor subunit 8) [includes: activator of rna decay (ec 3.1.4.-) (ard-1)]. [swissprot;acc:q12972]	Squared	99628.4	1.4861	148058
	son protein (son3) (negative regulatory element-binding protein) (nre- binding protein) (dbp-5) (bax antagonist selected in saccharomyces 1) (bass1) (protein c21orf50). [swissprot;acc:p18583]	Ranked	242.562	1.21228	294.053
132	autophagy protein 5-like (apg5-like) (apoptosis-specific protein). [swissprot;acc:q9h1y0]	Squared	24466.8	1.48606	36359.2
	forkhead box protein p3 (zinc finger protein jm2) (scurfin). [swissprot;acc:q9bzs1]	Measured	2980.35	1.33253	2236.61
	histone acetyltransferase type b catalytic subunit (ec 2.3.1.48). [swissprot;acc:o14929]	Rooted	55.0576	1.22451	44.963
	tob2 protein (transducer of erbb-2 2). [swissprot;acc:q14106]	Ranked	290	1.2069	350
133	gaba(a) receptor-associated protein; gaba(a)-receptor-associated protein. [refseq;acc:nm_007278]	Measured	17580.4	1.33225	23421.5
	gbp protein isoform a. [refseq;acc:nm_017870]	Squared	1726.55	1.46039	1182.25
	odd-skipped related 1; odz (odd oz/ten-m) related 1. [refseq;acc:nm_145260]	Rooted	55.5995	1.22316	45.4558
	tob1 protein (transducer of erbb-2 1). [swissprot;acc:p50616]	Ranked	290	1.2069	350
134	dab2 interacting protein; ngap-like protein; doc-2/dab2 interactive protein. [refseq;acc:nm_032552]
	dna polymerase epsilon p12 subunit (dna polymerase epsilon subunit 4). [swissprot;acc:q9nr33]	Rooted	54.7964	1.2218	44.849
	gaba-a receptor-associated protein. [sptrembl;acc:q9by60]	Measured	16426.1	1.32626	21785.2
	p66 alpha. [refseq;acc:nm_017660]	Squared	56306.5	1.45434	81888.8
135	20 kda nuclear cap binding protein (ncbp 20 kda subunit) (cbp20) (ncbp interacting protein 1) (nip1). [swissprot;acc:p52298]	Rooted	66.6101	1.21253	54.935
	apg3p; pc3-96 protein. [refseq;acc:nm_022488]	Measured	16426.1	1.32626	21785.2
	cytoplasmic polyadenylation element binding protein 4. [refseq;acc:nm_030627]	Ranked	290	1.2069	350
	transcription repressor p66 beta component of the mecp1 complex. [refseq;acc:nm_020699]	Squared	56306.5	1.45434	81888.8
136	adiponectin receptor 2. [refseq;acc:nm_024551]	Rooted	50.6469	1.21061	41.8357
	cytoplasmic polyadenylation element binding protein 3. [refseq;acc:nm_014912]	Ranked	290	1.2069	350
	nuclear transcription factor y subunit gamma (nf-y protein chain c) (nuclear factor yc) (nf-yc) (ccaat-binding transcription factor subunit c) (cbf-c) (transactivator hsm-1/2). [swissprot;acc:q13952]	Measured	4763.34	1.31556	3620.77
	tyrosine aminotransferase (ec 2.6.1.5) (l-tyrosine:2-oxoglutarate aminotransferase) (tat). [swissprot;acc:p17735]	Squared	56306.5	1.45434	81888.8
137	ccaat-binding transcription factor subunit b (cbf-b) (nf-y protein chain a) (nf-ya) (caat-box dna binding protein subunit a). [swissprot;acc:p23511]	Measured	4763.34	1.31556	3620.77
	cell division protein kinase 3 (ec 2.7.1.-). [swissprot;acc:q00526]	Squared	56215.8	1.45167	81606.8
	musashi 2 isoform a. [refseq;acc:nm_138962]	Rooted	66.2416	1.20486	54.9787
	ras gtpase-activating protein ngap (ras protein activator like 1). [swissprot;acc:q9ujf2]	Ranked	290	1.2069	350
138	kv channel interacting protein 1; vesicle apc-binding protein; a-type potassium channel modulatory protein 1. [refseq;acc:nm_014592]	Measured	2094.3	1.31555	2755.15
	musashi 1. [refseq;acc:nm_002442]	Rooted	66.2416	1.20486	54.9787

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.