Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Rank Gene Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 1001 to 1050 of 6456 in total
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
description
Rank
Network Comparison Type
red
green
network_comparison
carboxypeptidase b precursor. [refseq;acc:nm_020361] 509 Divided 177.698 190.239 1.07057
617 Subtracted 12.541
carboxypeptidase h precursor (ec 3.4.17.10) (cph) (carboxypeptidase e) (cpe) (enkephalin convertase) (prohormone processing carboxypeptidase). [swissprot;acc:p16870] 691 223.121 211.685 11.436
717 Divided 1.05402
carboxypeptidase n catalytic chain precursor (ec 3.4.17.3) (arginine carboxypeptidase) (kininase 1) (serum carboxypeptidase n) (scpn) (anaphylatoxin inactivator) (plasma carboxypeptidase b). [swissprot;acc:p15169] 689 Subtracted 11.436
715 Divided 1.05402
carcinoma related gene. [refseq;acc:nm_016041] 3179 0.00001 0.00001 1
Subtracted 0 0 0
carnitine o-acetyltransferase (ec 2.3.1.7) (carnitine acetylase) (cat). [swissprot;acc:p43155] 1692 217.624 214.69 2.934
1698 Divided 1.01367
carnitine o-palmitoyltransferase ii, mitochondrial precursor (ec 2.3.1.21) (cpt ii). [swissprot;acc:p23786] 2885 0.00001 0.00001 1
Subtracted 0 0 0
cartilage oligomeric matrix protein precursor (comp). [swissprot;acc:p49747] 141 239.991 269.238 29.247
226 Divided 1.12187
casein kinase i alpha s-like. [refseq;acc:nm_145203] 1427 Subtracted 229.459 225.237 4.222
1495 Divided 1.01874
casein kinase i, alpha isoform (ec 2.7.1.-) (cki-alpha) (ck1). [swissprot;acc:p48729] 1428 Subtracted 4.222
1496 Divided 1.01874
casein kinase i, delta isoform (ec 2.7.1.-) (cki-delta) (ckid). [swissprot;acc:p48730] 1679 Subtracted 227.125 224.164 2.961
1721 Divided 1.01321
casein kinase i, epsilon isoform (ec 2.7.1.-) (cki-epsilon) (ckie). [swissprot;acc:p49674] 1663 Subtracted 227.225 224.21 3.015
1710 Divided 1.01345
casein kinase i, gamma 1 isoform (ec 2.7.1.-) (cki-gamma 1). [swissprot;acc:q9hcp0] 2830 0.00001 0.00001 1
Subtracted 0 0 0
casein kinase i, gamma 2 isoform (ec 2.7.1.-) (cki-gamma 2). [swissprot;acc:p78368] 2986 Divided 0.00001 0.00001 1
Subtracted 0 0 0
casein kinase i, gamma 3 isoform (ec 2.7.1.-) (cki-gamma 3). [swissprot;acc:q9y6m4] 2901 Divided 0.00001 0.00001 1
Subtracted 0 0 0
casein kinase ii beta chain (ck ii) (phosvitin) (g5a). [swissprot;acc:p13862] 885 232.473 224.372 8.101
936 Divided 1.03611
casein kinase ii, alpha chain (ck ii) (ec 2.7.1.37). [swissprot;acc:p19138] 810 Subtracted 240.194 230.957 9.237
863 Divided 1.03999
casein kinase ii, alpha' chain (ck ii) (ec 2.7.1.37). [swissprot;acc:p19784] 811 Subtracted 9.237
864 Divided 1.03999
caspase-7 precursor (ec 3.4.22.-) (ice-like apoptotic protease 3) (ice-lap3) (apoptotic protease mch-3) (cmh-1). [swissprot;acc:p55210] 1165 Subtracted 233.942 228.46 5.482
1292 Divided 1.024
catenin (cadherin-associated protein), alpha-like 1; alpha-catulin. [refseq;acc:nm_003798] 1834 180.409 182.459 1.01136
1956 Subtracted 2.05
cathepsin b precursor (ec 3.4.22.1) (cathepsin b1) (app secretase). [swissprot;acc:p07858] 1667 Divided 214.898 211.898 1.01416
1672 Subtracted 3
cathepsin l precursor (ec 3.4.22.15) (major excreted protein) (mep). [swissprot;acc:p07711] 1390 214.717 219.157 4.44
1426 Divided 1.02068
cathepsin l2 precursor (ec 3.4.22.43) (cathepsin v) (cathepsin u). [swissprot;acc:o60911] 1389 Subtracted 4.44
1425 Divided 1.02068
caveolin-1. [swissprot;acc:q03135] 3099 0.00001 0.00001 1
Subtracted 0 0 0
caveolin-3 (m-caveolin). [swissprot;acc:p56539] 2779 Divided 0.00001 0.00001 1
Subtracted 0 0 0
cbf1 interacting corepressor. [refseq;acc:nm_004882] 555 227.86 213.945 13.915
572 Divided 1.06504

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/