MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Network Comparison Type	Gene	Rank	Value Type	description	network_comparison	red	Interaction Map	green	Filtered

Results: HTML CSV LaTeX

Showing element 451 to 500 of 1892 in total

Network Comparison Type  : Subtracted
network_comparison  : 0
red  : 0
Interaction Map  : High confidence
green  : 0
Filtered  : 1

Rank	Value Type	description
2868	Squared	eukaryotic initiation factor 4a-i (eif-4a-i) (eif4a-i). [swissprot;acc:p04765]
	Rooted
2869	Measured	phosphoribosyl pyrophosphate synthetase-associated protein 1 (prpp synthetase-associated protein 1) (39 kda phosphoribosypyrophosphate synthetase-associated protein) (pap39). [swissprot;acc:q14558]
	Ranked
	Squared
	Rooted
2870	Measured	adaptor protein with pleckstrin homology and src homology 2 domains. [refseq;acc:nm_020979]
	Ranked
	Squared
	Rooted
2871	Measured	vps28 protein homolog. [swissprot;acc:q9uk41]
	Ranked
	Squared
	Rooted
2872	Measured	transcriptional repressor nac1. [refseq;acc:nm_052876]
	Ranked
	Squared
	Rooted
2873	Measured	integrin beta-2 precursor (cell surface adhesion glycoproteins lfa- 1/cr3/p150,95 beta-subunit) (cd18) (complement receptor c3 beta- subunit). [swissprot;acc:p05107]
	Ranked
	Squared
	Rooted
2874	Measured	protein c21orf2 (c21orf-humf09g8.5) (yf5/a2). [swissprot;acc:o43822]
	Ranked
	Squared
	Rooted
2875	Measured	alpha crystallin a chain. [swissprot;acc:p02489]
	Ranked
	Squared
	Rooted
2876	Measured	high-affinity cgmp-specific 3',5'-cyclic phosphodiesterase 9a (ec 3.1.4.17). [swissprot;acc:o76083]
	Ranked
	Squared
	Rooted
2877	Measured	runt-related transcription factor 1 (core-binding factor, alpha 2 subunit) (cbf-alpha 2) (acute myeloid leukemia 1 protein) (oncogene aml-1) (polyomavirus enhancer binding protein 2 alpha b subunit) (pebp2-alpha b) (pea2-alpha b) (sl3-3 enhancer factor 1 alpha b subunit) (sl3/akv core-binding factor alpha b subunit). [swissprot;acc:q01196]
	Ranked
	Squared
	Rooted
2878	Measured	nadh-ubiquinone oxidoreductase 49 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-49kd) (ci-49kd). [swissprot;acc:o75306]
	Ranked
	Squared
	Rooted
2879	Measured	spir-2 protein (fragment). [sptrembl;acc:q8wwl2]
	Ranked
	Squared
	Rooted
2880	Measured	microtubule-interacting protein that associates with traf3; interleukin 13 receptor alpha 1-binding protein-1. [refseq;acc:nm_015650]
	Ranked
	Squared
	Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.