Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis - Divided Values

Type II network, divided values. Interestingly most of the proteins in the first 100 positions in this table would occur in the divided ranks table between position 100 and 200, indicating a difference in emphasis between the two simulations but not in the overall function. The fully annotated table, include Ensembl gene identifiers and network values can be found in the supplementary data.


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
green description Rank Gene Interaction Map Value Type Network Comparison Type Filtered red network_comparison
Results: HTML CSV LaTeX Showing element 501 to 550 of 12912 in total
green  : 0.00001
Interaction Map  : High confidence
Network Comparison Type  : Divided
Filtered  : 1
red  : 0.00001
network_comparison  : 1
description
Rank
Value Type
fibrillin 3. [refseq;acc:nm_032447] 2939 Measured
Ranked
Squared
Rooted
flap endonuclease-1 (ec 3.-.-.-) (maturation factor 1) (mf1). [swissprot;acc:p39748] 2831 Measured
Ranked
Squared
Rooted
fructose-bisphosphate aldolase a (ec 4.1.2.13) (muscle-type aldolase) (lung cancer antigen ny-lu-1). [swissprot;acc:p04075] 2907 Measured
Ranked
Squared
Rooted
fructose-bisphosphate aldolase b (ec 4.1.2.13) (liver-type aldolase). [swissprot;acc:p05062] 2973 Measured
Ranked
Squared
Rooted
fructose-bisphosphate aldolase c (ec 4.1.2.13) (brain-type aldolase). [swissprot;acc:p09972] 3087 Measured
Ranked
Squared
Rooted
fyve-finger-containing rab5 effector protein rabenosyn-5. [refseq;acc:nm_022340] 2998 Measured
Ranked
Squared
Rooted
g protein-coupled receptor 66. [refseq;acc:nm_006056] 2815 Measured
Ranked
Squared
Rooted
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284] 3101 Measured
Ranked
Squared
Rooted
gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488] 3125 Measured
Ranked
Squared
Rooted
geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611] 2963 Measured
Ranked
Squared
Rooted
glioma pathogenesis-related protein (glipr) (rtvp-1 protein). [swissprot;acc:p48060] 2953 Measured
Ranked
Squared
Rooted
glioma tumor suppressor candidate region gene 2 protein (p60). [swissprot;acc:q9nzm5] 3104 Measured
Ranked
Squared
Rooted
glioma-amplified sequence-41; numa binding protein 1. [refseq;acc:nm_006530] 3007 Measured
Ranked

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/