Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Value Type green Filtered Rank Gene description Interaction Map network_comparison red Network Comparison Type
Results: HTML CSV LaTeX Showing element 3682 to 3731 of 19268 in total
Value Type  : Ranked
Filtered  : 1
green
Rank
description
Interaction Map
network_comparison
red
Network Comparison Type
195.708 1954 sipl protein. [refseq;acc:nm_018269] Low confidence 3.869 199.577 Subtracted
2314 ubiquitin-conjugating enzyme e2-17 kda 2 (ec 6.3.2.19) (ubiquitin- protein ligase) (ubiquitin carrier protein) (e2(17)kb 2). [swissprot;acc:p51669] High confidence 1.00496 194.743 Divided
2340 0.965 Subtracted
195.713 1174 diaphanous protein homolog 3 (diaphanous-related formin 3) (drf3) (fragment). [swissprot;acc:q9nsv4] Low confidence 1.02322 200.258 Divided
1183 4.545 Subtracted
3540 serine/threonine protein phosphatase 2a, 65 kda regulatory subunit a, beta isoform (pp2a, subunit a, pr65-beta isoform) (pp2a, subunit a, r1-beta isoform). [swissprot;acc:p30154] 1.0147 198.59 Divided
3582 2.877 Subtracted
195.715 1087 cab2. [refseq;acc:nm_033419] 1.02381 200.375 Divided
1095 4.66 Subtracted
195.716 1084 elovl family member 6, elongation of long chain fatty acids (fen1/elo2, sur4/elo3-like, yeast); long-chain fatty-acyl elongase. [refseq;acc:nm_024090] 1.02383 200.38 Divided
1092 4.664 Subtracted
195.718 2361 ubiquinone biosynthesis monooxgenase coq6 (ec 1.14.13.-) (cgi-10). [swissprot;acc:q9y2z9] 1.01858 199.354 Divided
2405 3.636 Subtracted
195.725 1631 carnitine o-palmitoyltransferase i, mitochondrial muscle isoform (ec 2.3.1.21) (cpt i) (cpti-m) (carnitine palmitoyltransferase i like protein). [swissprot;acc:q92523] 1.02078 199.793 Divided
1644 4.068 Subtracted
195.729 591 g10 protein homolog (edg-2). [swissprot;acc:p41223] 1.03035 201.67 Divided
595 5.941 Subtracted
195.732 3081 homeobox protein prh (hematopoietically expressed homeobox) (homeobox protein hex). [swissprot;acc:q03014] 1.01653 198.968 Divided
3118 3.236 Subtracted
195.735 3265 synaptic glycoprotein sc2. [swissprot;acc:q9nz01] 1.01576 198.82 Divided
3342 3.085 Subtracted
195.742 476 tissue alpha-l-fucosidase precursor (ec 3.2.1.51) (alpha-l-fucosidase i) (alpha-l-fucoside fucohydrolase). [swissprot;acc:p04066] 1.03336 202.271 Divided
493 6.529 Subtracted
195.758 1363 junctional adhesion molecule 1 precursor (jam) (platelet adhesion molecule 1) (pam-1) (platelet f11 receptor). [swissprot;acc:q9y624] 1.022 200.065 Divided
1407 4.307 Subtracted
195.761 1950 hepatoma-derived growth factor-related protein 2. [refseq;acc:nm_032631] 1.01963 199.603 Divided
1951 cgi-142; hepatoma-derived growth factor 2. [refseq;acc:nm_016073]
1952 pc4 and sfrs1 interacting protein 2; pc4 and sfrs1 interacting protein 1; transcriptional coactivator p52/p75. [refseq;acc:nm_033222]
1953 hepatoma-derived growth factor (hdgf) (high-mobility group protein 1- like 2) (hmg-1l2). [swissprot;acc:p51858]
1954 pwwp domain containing 1; hdgf (hepatoma-derived growth factor) like. [refseq;acc:nm_138574]
1955 probable atp-dependent rna helicase p54 (oncogene rck) (dead-box protein 6). [swissprot;acc:p26196]
1956 rw1 protein (fragment). [swissprot;acc:q92545]
1992 hepatoma-derived growth factor-related protein 2. [refseq;acc:nm_032631] 3.842 Subtracted
1993 cgi-142; hepatoma-derived growth factor 2. [refseq;acc:nm_016073]
1994 pc4 and sfrs1 interacting protein 2; pc4 and sfrs1 interacting protein 1; transcriptional coactivator p52/p75. [refseq;acc:nm_033222]
1995 hepatoma-derived growth factor (hdgf) (high-mobility group protein 1- like 2) (hmg-1l2). [swissprot;acc:p51858]
1997 pwwp domain containing 1; hdgf (hepatoma-derived growth factor) like. [refseq;acc:nm_138574]
1998 probable atp-dependent rna helicase p54 (oncogene rck) (dead-box protein 6). [swissprot;acc:p26196]
2000 rw1 protein (fragment). [swissprot;acc:q92545]
195.763 1991 26s protease regulatory subunit 6b (mip224) (mb67 interacting protein) (tat-binding protein-7) (tbp-7). [swissprot;acc:p43686] 1.01951 199.582 Divided
2044 3.819 Subtracted
195.769 4027 homeobox protein dlx-5. [swissprot;acc:p56178] 1.01152 198.024 Divided
4050 2.255 Subtracted
195.773 855 hydroxyacylglutathione hydrolase (ec 3.1.2.6) (glyoxalase ii) (glx ii). [swissprot;acc:q16775] 1.02579 200.822 Divided
863 5.049 Subtracted
195.778 475 fucosidase, alpha-l- 2, plasma. [refseq;acc:nm_032020] 1.03337 202.311 Divided
490 6.533 Subtracted
4023 homeobox protein dlx-3. [swissprot;acc:o60479] 1.01154 198.038 Divided
4047 2.26 Subtracted
4125 conserved oligomeric golgi complex component 1. [swissprot;acc:q8wtw3] 1.01062 197.858 Divided

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/