Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.


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Filtered green description Value Type network_comparison Rank Gene Interaction Map red Network Comparison Type
Results: HTML CSV LaTeX Showing element 1 to 50 of 38536 in total
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Network Comparison Type Divided
description Value Type network_comparison Rank Interaction Map red brca1 associated protein. [source:refseq;acc:nm_006768] Measured 1 502 High confidence 0.00001 brca1 associated protein. [source:refseq;acc:nm_006768] Ranked 1 502 High confidence 0.00001 brca1 associated protein. [source:refseq;acc:nm_006768] Squared 1 502 High confidence 0.00001 brca1 associated protein. [source:refseq;acc:nm_006768] Rooted 1 502 High confidence 0.00001 carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [source:refseq;acc:nm_021615] Measured 3700000 22 Low confidence 37 carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [source:refseq;acc:nm_021615] Squared 32402.4 5 Low confidence 0.324024 carbohydrate (n-acetylglucosamine 6-o) sulfotransferase 6; macular dystrophy, corneal, 1; carbohydate sulfotransferase 6; corneal n-acetylglucosamine 6-sulfotransferase. [source:refseq;acc:nm_021615] Rooted 608276 6 Low confidence 6.08276 carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [source:refseq;acc:nm_004267] Measured 3700000 23 Low confidence 37 carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [source:refseq;acc:nm_004267] Squared 32402.4 6 Low confidence 0.324024 carbohydrate (n-acetylglucosamine-6-o) sulfotransferase 2; carbohydrate (chondroitin 6/keratan) sulfotransferase 2. [source:refseq;acc:nm_004267] Rooted 608276 7 Low confidence 6.08276 cobw-like protein. [source:refseq;acc:nm_018491] Measured 1 839 Low confidence 0.00001 cobw-like protein. [source:refseq;acc:nm_018491] Ranked 1 839 Low confidence 0.00001 cobw-like protein. [source:refseq;acc:nm_018491] Squared 1 839 Low confidence 0.00001 cobw-like protein. [source:refseq;acc:nm_018491] Rooted 1 839 Low confidence 0.00001 dok-like protein. [source:refseq;acc:nm_024872] Measured 3500000 31 High confidence 35 dok-like protein. [source:refseq;acc:nm_024872] Squared 28994.1 13 High confidence 0.289941 dok-like protein. [source:refseq;acc:nm_024872] Rooted 591608 13 High confidence 5.91608 ero1-like. [source:refseq;acc:nm_014584] Measured 8200000 20 High confidence 82 ero1-like. [source:refseq;acc:nm_014584] Squared 159148 8 High confidence 1.59148 ero1-like. [source:refseq;acc:nm_014584] Rooted 905539 8 High confidence 9.05539 gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [source:refseq;acc:nm_080920] Measured 1 838 Low confidence 0.00001 gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [source:refseq;acc:nm_080920] Ranked 1 838 Low confidence 0.00001 gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [source:refseq;acc:nm_080920] Squared 1 838 Low confidence 0.00001 gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [source:refseq;acc:nm_080920] Rooted 1 838 Low confidence 0.00001 gamma-glutamyltransferase. [source:sptrembl;acc:q14390] Measured 1 841 Low confidence 0.00001 gamma-glutamyltransferase. [source:sptrembl;acc:q14390] Ranked 1 841 Low confidence 0.00001 gamma-glutamyltransferase. [source:sptrembl;acc:q14390] Squared 1 841 Low confidence 0.00001 gamma-glutamyltransferase. [source:sptrembl;acc:q14390] Rooted 1 841 Low confidence 0.00001 gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [source:swissprot;acc:p19440] Measured 1 842 Low confidence 0.00001 gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [source:swissprot;acc:p19440] Ranked 1 842 Low confidence 0.00001 gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [source:swissprot;acc:p19440] Squared 1 842 Low confidence 0.00001 gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [source:swissprot;acc:p19440] Rooted 1 842 Low confidence 0.00001 gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [source:swissprot;acc:p36268] Measured 1 837 Low confidence 0.00001 gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [source:swissprot;acc:p36268] Ranked 1 837 Low confidence 0.00001 gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [source:swissprot;acc:p36268] Squared 1 837 Low confidence 0.00001 gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [source:swissprot;acc:p36268] Rooted 1 837 Low confidence 0.00001 gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [source:swissprot;acc:p36269] Measured 1 843 Low confidence 0.00001 gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [source:swissprot;acc:p36269] Ranked 1 843 Low confidence 0.00001 gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [source:swissprot;acc:p36269] Squared 1 843 Low confidence 0.00001 gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [source:swissprot;acc:p36269] Rooted 1 843 Low confidence 0.00001 h2a histone family, member j isoform 1. [source:refseq;acc:nm_018267] Measured 1 501 High confidence 0.00001 h2a histone family, member j isoform 1. [source:refseq;acc:nm_018267] Squared 1 501 High confidence 0.00001 h2a histone family, member j isoform 1. [source:refseq;acc:nm_018267] Rooted 1 501 High confidence 0.00001 histone h2a.a (h2a/a) (h2a.2). [source:swissprot;acc:p28001] Measured 1 495 High confidence 0.00001 histone h2a.a (h2a/a) (h2a.2). [source:swissprot;acc:p28001] Squared 1 495 High confidence 0.00001 histone h2a.a (h2a/a) (h2a.2). [source:swissprot;acc:p28001] Rooted 1 495 High confidence 0.00001 histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [source:swissprot;acc:p02261] Measured 1 494 High confidence 0.00001 histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [source:swissprot;acc:p02261] Squared 1 494 High confidence 0.00001 histone h2a.c/d/i/n/p (h2a.1) (h2a/c) (h2a/d) (h2a/i) (h2a/n) (h2a/p) (h2a.1b). [source:swissprot;acc:p02261] Rooted 1 494 High confidence 0.00001 histone h2a; h2a histone family, member r. [source:refseq;acc:nm_170745] Measured 1 497 High confidence 0.00001 Legend: - Rank is the rank after comparing the two networks - Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions. - Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them - Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions. - Filtered specifies whether we only included the high confidence microarry measurements or not.

- http://analysis.yellowcouch.org/