MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

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description	Value Type	Rank	Gene	Network Comparison Type	Filtered	Interaction Map	red	green	network_comparison

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Showing element 601 to 650 of 29840 in total

Interaction Map  : High confidence

description	Value Type	Rank	Network Comparison Type	Filtered	red	green	network_comparison
40s ribosomal protein s16. [swissprot;acc:p17008]	Measured	2448	Divided	1	3730.53	3611.05	1.03309
		2528	Subtracted				119.48
	Ranked	326			241.828	263.62	21.792
		391	Divided				1.09011
	Squared	1784			13244.1	14564.4	1.09969
		2407	Subtracted				1320.3
	Rooted	534	Divided		50.8036	46.8198	1.08509
		830	Subtracted				3.9838
40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]	Measured	2437	Divided		3708.67	3584.47	1.03465
		2521	Subtracted				124.2
	Ranked	324			242.238	264.11	21.872
		387	Divided				1.09029
	Squared	1824			13145.4	14424.1	1.09727
		2419	Subtracted				1278.7
	Rooted	531	Divided		50.6537	46.6413	1.08603
		825	Subtracted				4.0124
40s ribosomal protein s19. [swissprot;acc:p39019]	Measured	807	Divided		4708.61	5226.71	1.11003
		1099	Subtracted				518.1
	Ranked	820			234.025	224.958	9.067
		861	Divided				1.04031
	Squared	1129			18854.4	21540.4	1.14246
		1478	Subtracted				2686
	Rooted	771	Divided		55.6817	59.3786	1.06639
		907	Subtracted				3.6969
40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]	Measured	143		0	1499.4	1735.23	235.83
		222	Divided				1.15728
		2242		1	3670.45	3504.91	1.04723
		2450	Subtracted				165.54
	Ranked	176		0	11935.1	10592.8	1342.3
		186	Divided				1.12672
		269	Subtracted	1	241.625	265.136	23.511
		344	Divided				1.0973
	Squared	91	Subtracted	0	4734.34	6172.1	1437.76
		241	Divided				1.30369
		1954		1	12789.3	13977.2	1.09288
		2468	Subtracted				1187.9
	Rooted	174		0	23.1768	26.17	2.9932
		225	Divided				1.12915
		461		1	50.6156	46.2239	1.09501
		731	Subtracted				4.3917
40s ribosomal protein s20. [swissprot;acc:p17075]	Measured	2211	Divided		3590.56	3422.6	1.04907
		2436	Subtracted				167.96
	Ranked	251			243.5	267.21	23.71
		342	Divided				1.09737
	Squared	1926			12452.6	13619.9	1.09374
		2485	Subtracted				1167.3
	Rooted	425	Divided		50.0161	45.5318	1.09849
		707	Subtracted				4.4843
40s ribosomal protein s21. [swissprot;acc:p35265]	Measured	2374			5078.5	5275.76	197.26
		2403	Divided				1.03884

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.