MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

green	description	Filtered	Gene	red	Rank	Interaction Map	Value Type	network_comparison	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 401 to 450 of 77072 in total

green  : 0
Interaction Map  : High confidence
Network Comparison Type  : Subtracted

description	Filtered	red	Rank	Value Type	network_comparison
developmentally regulated gtp-binding protein 2 (drg 2). [swissprot;acc:p55039]	1	0	3092	Squared	0
				Rooted
dgcr8 protein (digeorge syndrome critical region 8). [swissprot;acc:q8wyq5]			3006	Measured
				Ranked
				Squared
				Rooted
dj579f20.1 (high-mobility group (nonhistone chromosomal) protein 1-like 1). [sptrembl;acc:q9nqj4]			3025	Measured
				Ranked
				Squared
				Rooted
dna excision repair protein ercc-1. [swissprot;acc:p07992]			3216	Measured
				Ranked
				Squared
				Rooted
dna ligase i (ec 6.5.1.1) (polydeoxyribonucleotide synthase [atp]). [swissprot;acc:p18858]			3103	Measured
				Ranked
				Squared
				Rooted
dna ligase iv (ec 6.5.1.1) (polydeoxyribonucleotide synthase [atp]). [swissprot;acc:p49917]			2808	Measured
				Ranked
				Squared
				Rooted
dna methyltransferase 1-associated protein 1 (dnmt1-associated protein 1) (dnmap1). [swissprot;acc:q9npf5]			2796	Measured
				Ranked
				Squared
				Rooted
dna mismatch repair protein msh2. [swissprot;acc:p43246]			3151	Measured
				Ranked
				Squared
				Rooted
dna mismatch repair protein msh6 (muts-alpha 160 kda subunit) (g/t mismatch binding protein) (gtbp) (gtmbp) (p160). [swissprot;acc:p52701]			3045	Measured
				Ranked
				Squared
				Rooted
dna replication licensing factor mcm8 (minichromosome maintenance 8). [swissprot;acc:q9uja3]			3011	Measured
				Ranked
				Squared
				Rooted
dna-repair protein complementing xp-a cells (xeroderma pigmentosum group a complementing protein). [swissprot;acc:p23025]			2971	Measured
				Ranked
				Squared
				Rooted
dna-repair protein complementing xp-f cell (xeroderma pigmentosum group f complementing protein) (dna excision repair protein ercc-4). [swissprot;acc:q92889]			2801	Measured
				Ranked
				Squared
				Rooted
dok-like protein. [refseq;acc:nm_024872]	0	0.289941	467	Squared	0.289941
		5.91608	74	Rooted	5.91608
		35	386	Measured	35
double-stranded rna-binding zinc finger protein jaz. [refseq;acc:nm_012279]	1	0	3054		0

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.