Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
description Filtered Rank Value Type Gene Network Comparison Type green Interaction Map network_comparison red
Results: HTML CSV LaTeX Showing element 3180 to 3229 of 9634 in total
Value Type  : Measured
Network Comparison Type  : Divided
description
Filtered
Rank
green
Interaction Map
network_comparison
red
galectin-8 (gal-8) (prostate carcinoma tumor antigen 1) (pcta-1) (po66 carbohydrate-binding protein) (po66-cbp). [swissprot;acc:o00214] 1 2641 8152.91 Low confidence 1.02975 7917.39
galectin-9 (hom-hd-21) (ecalectin). [swissprot;acc:o00182] 570 8364.68 1.04596 7997.15
973 8566.29 High confidence 1.09682 7810.11
gamma adducin (adducin-like protein 70). [swissprot;acc:q9uey8] 1365 6255.04 1.07862 5799.14
2718 7960.07 Low confidence 1.02943 7732.51
gamma enolase (ec 4.2.1.11) (2-phospho-d-glycerate hydro-lyase) (neural enolase) (nse) (enolase 2). [swissprot;acc:p09104] 943 7241 High confidence 1.09746 6597.98
4083 8082.09 Low confidence 1.02155 7911.57
gamma-aminobutyric acid type b receptor, subunit 2 precursor (gaba-b receptor 2) (gaba-b-r2) (gb2) (gababr2) (g protein-coupled receptor 51) (gpr 51) (hg20). [swissprot;acc:o75899] 1429 8293.26 1.03444 8017.16
gamma-aminobutyric-acid receptor alpha-1 subunit precursor (gaba(a) receptor). [swissprot;acc:p14867] 587 7644.63 High confidence 1.13425 6739.83
1907 8240 Low confidence 1.03253 7980.36
gamma-aminobutyric-acid receptor alpha-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p47869] 580 7644.63 High confidence 1.13425 6739.83
1901 8240 Low confidence 1.03253 7980.36
gamma-aminobutyric-acid receptor alpha-3 subunit precursor (gaba(a) receptor). [swissprot;acc:p34903] 588 7644.63 High confidence 1.13425 6739.83
1908 8240 Low confidence 1.03253 7980.36
gamma-aminobutyric-acid receptor alpha-4 subunit precursor (gaba(a) receptor). [swissprot;acc:p48169] 584 7644.63 High confidence 1.13425 6739.82
1904 8240.01 Low confidence 1.03253 7980.37
gamma-aminobutyric-acid receptor alpha-6 subunit precursor (gaba(a) receptor). [swissprot;acc:q16445] 581 7644.63 High confidence 1.13425 6739.82
1902 8240.01 Low confidence 1.03253 7980.37
gamma-aminobutyric-acid receptor epsilon subunit precursor (gaba(a) receptor). [swissprot;acc:p78334] 585 7644.63 High confidence 1.13425 6739.82
1906 8240.01 Low confidence 1.03253 7980.37
gamma-aminobutyric-acid receptor gamma-1 subunit precursor (gaba(a) receptor). [swissprot;acc:q8n1c3] 579 7644.62 High confidence 1.13425 6739.82
1897 8240.05 Low confidence 1.03254 7980.4
gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507] 582 7644.62 High confidence 1.13425 6739.82
1898 8240.05 Low confidence 1.03254 7980.4
gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928] 577 7644.62 High confidence 1.13425 6739.81
1896 8240.09 Low confidence 1.03254 7980.43
gamma-butyrobetaine,2-oxoglutarate dioxygenase (ec 1.14.11.1) (gamma-butyrobetaine hydroxylase) (gamma-bbh). [swissprot;acc:o75936] 1339 8381.53 1.03508 8097.5
1348 6640.77 High confidence 1.07921 6153.36
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920] 0 838 0.00001 Low confidence 1 0.00001
1 5030
gamma-glutamyltransferase. [sptrembl;acc:q14390] 0 841
1 5053
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440] 0 842
1 5054
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268] 0 837
1 5021
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269] 0 843
1 5055
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284] 3101 High confidence
4766 8337.89 Low confidence 1.01275 8232.92
gamma-sarcoglycan (gamma-sg) (35 kda dystrophin-associated glycoprotein) (35dag). [swissprot;acc:q13326] 741 6434.78 High confidence 1.11554 5768.32
2151 8022.11 Low confidence 1.03162 7776.2
gamma-snap-associated factor 1; rab11-interacting protein. [refseq;acc:nm_015470] 1253 8222.82 1.03574 7939.04
1450 6031.05 High confidence 1.07659 5602.01
gamma-soluble nsf attachment protein (snap-gamma) (n-ethylmaleimide- sensitive factor attachment protein, gamma). [swissprot;acc:q99747] 500 4093.05 1.1441 4682.87
3057 8193.5 Low confidence 1.02784 7971.58
gamma-tubulin complex component 2 (gcp-2) (spindle pole body protein spc97 homolog) (hspc97) (hgcp2) (h103p). [swissprot;acc:q9bsj2] 3384 8266.31 1.02652 8052.79
gamma-tubulin complex component 3 (gcp-3) (spindle pole body protein spc98 homolog) (hspc98) (hgcp3) (h104p). [swissprot;acc:q96cw5] 3432 8248.53 1.02635 8036.77
gamma-tubulin complex component 5 (gcp-5). [swissprot;acc:q96rt8] 3108 8249.36 1.02761 8027.74
ganglioside induced differentiation associated protein 2; likely ortholog of mouse ganglioside-induced differentiation-associated-protein 2. [refseq;acc:nm_017686] 0 833 9357.07 1.0002 9355.21

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/