Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.


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description Gene Rank Value Type Network Comparison Type Interaction Map Filtered red green network_comparison
Results: HTML CSV LaTeX Showing element 3180 to 3229 of 9634 in total
Value Type  : Ranked
Network Comparison Type  : Divided
description
Rank
Interaction Map
Filtered
red
green
network_comparison
galectin-8 (gal-8) (prostate carcinoma tumor antigen 1) (pcta-1) (po66 carbohydrate-binding protein) (po66-cbp). [swissprot;acc:o00214] 2637 Low confidence 1 203.204 199.656 1.01777
galectin-9 (hom-hd-21) (ecalectin). [swissprot;acc:o00182] 2122 High confidence 206.473 207.911 1.00696
2503 Low confidence 198.665 195.119 1.01817
gamma adducin (adducin-like protein 70). [swissprot;acc:q9uey8] 1467 205.917 201.572 1.02156
1934 High confidence 224.264 222.055 1.00995
gamma enolase (ec 4.2.1.11) (2-phospho-d-glycerate hydro-lyase) (neural enolase) (nse) (enolase 2). [swissprot;acc:p09104] 2360 207.186 208.046 1.00415
4637 Low confidence 201.997 200.674 1.00659
gamma-aminobutyric acid type b receptor, subunit 2 precursor (gaba-b receptor 2) (gaba-b-r2) (gb2) (gababr2) (g protein-coupled receptor 51) (gpr 51) (hg20). [swissprot;acc:o75899] 832 204.064 198.895 1.02599
gamma-aminobutyric-acid receptor alpha-1 subunit precursor (gaba(a) receptor). [swissprot;acc:p14867] 628 High confidence 214.256 202.14 1.05994
2418 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor alpha-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p47869] 621 High confidence 214.256 202.14 1.05994
2412 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor alpha-3 subunit precursor (gaba(a) receptor). [swissprot;acc:p34903] 629 High confidence 214.256 202.14 1.05994
2419 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor alpha-4 subunit precursor (gaba(a) receptor). [swissprot;acc:p48169] 625 High confidence 214.256 202.14 1.05994
2416 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor alpha-6 subunit precursor (gaba(a) receptor). [swissprot;acc:q16445] 622 High confidence 214.256 202.14 1.05994
2413 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor epsilon subunit precursor (gaba(a) receptor). [swissprot;acc:p78334] 626 High confidence 214.256 202.14 1.05994
2417 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor gamma-1 subunit precursor (gaba(a) receptor). [swissprot;acc:q8n1c3] 620 High confidence 214.256 202.14 1.05994
2411 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor gamma-2 subunit precursor (gaba(a) receptor). [swissprot;acc:p18507] 623 High confidence 214.256 202.14 1.05994
2415 Low confidence 203.126 199.444 1.01846
gamma-aminobutyric-acid receptor gamma-3 subunit precursor (gaba(a) receptor). [swissprot;acc:q99928] 618 High confidence 214.256 202.139 1.05994
2404 Low confidence 203.126 199.443 1.01847
gamma-butyrobetaine,2-oxoglutarate dioxygenase (ec 1.14.11.1) (gamma-butyrobetaine hydroxylase) (gamma-bbh). [swissprot;acc:o75936] 876 203.744 198.658 1.0256
1842 High confidence 212.455 210.113 1.01115
gamma-glutamyltransferase-like activity 4; gamma-glutamyltranspeptidase-like. [refseq;acc:nm_080920] 838 Low confidence 0 0.00001 0.00001 1
5029 1
gamma-glutamyltransferase. [sptrembl;acc:q14390] 841 0
5053 1
gamma-glutamyltranspeptidase 1 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 1) (cd224 antigen). [swissprot;acc:p19440] 842 0
5054 1
gamma-glutamyltranspeptidase 2 (ec 2.3.2.2) (gamma-glutamyltransferase 2) (fragment). [swissprot;acc:p36268] 837 0
5020 1
gamma-glutamyltranspeptidase 5 precursor (ec 2.3.2.2) (gamma- glutamyltransferase 5) (ggt-rel). [swissprot;acc:p36269] 843 0
5055 1
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284] 3101 High confidence
4028 Low confidence 200.61 198.325 1.01152
gamma-sarcoglycan (gamma-sg) (35 kda dystrophin-associated glycoprotein) (35dag). [swissprot;acc:q13326] 1026 206.781 201.874 1.02431
1181 High confidence 218.186 212.672 1.02593
gamma-snap-associated factor 1; rab11-interacting protein. [refseq;acc:nm_015470] 1817 220.462 217.926 1.01164
2278 Low confidence 201.767 198.041 1.01881
gamma-soluble nsf attachment protein (snap-gamma) (n-ethylmaleimide- sensitive factor attachment protein, gamma). [swissprot;acc:q99747] 166 High confidence 209.299 249.187 1.19058
3246 Low confidence 201.31 198.167 1.01586
gamma-tubulin complex component 2 (gcp-2) (spindle pole body protein spc97 homolog) (hspc97) (hgcp2) (h103p). [swissprot;acc:q9bsj2] 2916 200.725 197.365 1.01702
gamma-tubulin complex component 3 (gcp-3) (spindle pole body protein spc98 homolog) (hspc98) (hgcp3) (h104p). [swissprot;acc:q96cw5] 3488 200.524 197.562 1.01499
gamma-tubulin complex component 5 (gcp-5). [swissprot;acc:q96rt8] 3065 200.314 197.051 1.01656
ganglioside induced differentiation associated protein 2; likely ortholog of mouse ganglioside-induced differentiation-associated-protein 2. [refseq;acc:nm_017686] 800 0 9389.91 9441.84 1.00553

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/