MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Filtered	Value Type	Gene	network_comparison	green	Rank	description	Interaction Map	red	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 501 to 550 of 77072 in total

Filtered  : 0
Value Type  : Measured
Network Comparison Type  : Divided

network_comparison	green	Rank	description	Interaction Map	red
1.06041	989.438	370	dna directed rna polymerase ii polypeptide j-related gene isoform 3; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_032959]	High confidence	1049.21
1.06044	988.882	369	dna directed rna polymerase ii polypeptide j-related gene isoform 1; rpb11b1alpha protein; rpb11b1beta; dna-directed rna polymerase ii subunit 11. [refseq;acc:nm_145325]		1048.65
1.06077	5606.29	368	galectin-4 (lactose-binding lectin 4) (l-36 lactose binding protein) (l36lbp) (antigen ny-co-27). [swissprot;acc:p56470]		5946.96
1.06087	3301.23	497	ero1-like. [refseq;acc:nm_014584]	Low confidence	3111.8
1.061	856.162	496	elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]		908.392
1.06104	3353.47	493	cell adhesion molecule with homology to l1cam precursor; neural cell adhesion molecule; cell adhesion molecule l1-like; l1 cell adhesion molecule 2. [refseq;acc:nm_006614]		3160.54
		494	neural cell adhesion molecule l1 precursor (n-cam l1) (cd171 antigen). [swissprot;acc:p32004]
		495	transcription initiation factor tfiid 31 kda subunit (tafii-31) (tafii-32) (tafii32). [swissprot;acc:q16594]
1.0612	2059.13	492	hydroxyindole o-methyltransferase (ec 2.1.1.4) (hiomt) (acetylserotonin o-methyltransferase) (asmt). [swissprot;acc:p46597]		1940.37
1.06127	1534.89	491	uridine kinase-like 1. [swissprot;acc:q9nwz5]		1446.27
1.06151	2164.92	367	e1a binding protein p400; p400 swi2/snf2-related protein; cagh32 protein; trinucleotide repeat containing 12. [refseq;acc:nm_015409]	High confidence	2039.47
1.06238	2742.78	490	adp-ribosylation factor gtpase-activating protein 3 (arf gap 3). [swissprot;acc:q9np61]	Low confidence	2913.87
1.06242	3276.76	489	trna selenocysteine associated protein. [refseq;acc:nm_017846]		3084.23
1.0625	51	350	melanoma antigen, family d, 4 isoform 1; mage1 protein; mage-e1 protein; maged4 protein. [refseq;acc:nm_030801]	High confidence	48
		351	melanoma-associated antigen 3 (mage-3 antigen) (antigen mz2-d). [swissprot;acc:p43357]
		352	melanoma-associated antigen 11 (mage-11 antigen). [swissprot;acc:p43364]
		353	melanoma-associated antigen 2 (mage-2 antigen). [swissprot;acc:p43356]
		354	hepatocellular carcinoma-associated protein hca1. [refseq;acc:nm_020932]
		355	melanoma-associated antigen 6 (mage-6 antigen) (mage3b). [swissprot;acc:p43360]
		356	melanoma-associated antigen d1 (mage-d1 antigen) (neurotrophin receptor-interacting mage homolog) (pro2292). [swissprot;acc:q9y5v3]
		357	melanoma-associated antigen f1 (mage-f1 antigen). [swissprot;acc:q9hay2]
		358	melanoma-associated antigen 4 (mage-4 antigen) (mage-x2) (mage-41). [swissprot;acc:p43358]
		359	melanoma-associated antigen 9 (mage-9 antigen). [swissprot;acc:p43362]
		360	melanoma-associated antigen 8 (mage-8 antigen). [swissprot;acc:p43361]
		361	melanoma-associated antigen c1 (mage-c1 antigen) (cancer-testis antigen ct7). [swissprot;acc:o60732]
		362	melanoma-associated antigen 12 (mage-12 antigen) (mage12f). [swissprot;acc:p43365]
		363	melanoma-associated antigen 1 (mage-1 antigen) (antigen mz2-e). [swissprot;acc:p43355]
		364	melanoma-associated antigen 10 (mage-10 antigen). [swissprot;acc:p43363]
		365	melanoma-associated antigen b1 (mage-b1 antigen) (mage-xp antigen) (dss-ahc critical interval mage superfamily 10) (dam10). [swissprot;acc:p43366]
		366	melanoma-associated antigen d2 (mage-d2 antigen) (breast cancer associated gene 1 protein) (bcg-1) (11b6) (hepatocellular carcinoma associated protein jcl-1). [swissprot;acc:q9unf1]
1.06293	2467.83	488	cytochrome p450 3a7 (ec 1.14.14.1) (cypiiia7) (p450-hfla). [swissprot;acc:p24462]	Low confidence	2321.73
1.06327	2155.63	487	heat shock 70 kda protein 1 (hsp70.1) (hsp70-1/hsp70-2). [swissprot;acc:p08107]		2292.02
1.06361	580.798	486	espin. [refseq;acc:nm_031475]		617.742
1.06422	339.779	485	phosphatidylinositol-4-phosphate 3-kinase c2 domain-containing beta polypeptide (ec 2.7.1.154) (phosphoinositide 3-kinase-c2-beta) (ptdins-3-kinase c2 beta) (pi3k-c2beta) (c2-pi3k). [swissprot;acc:o00750]		361.601
1.06475	1431.5	484	adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]		1344.45
1.0651	3982.2	483	myocyte-specific enhancer factor 2a (serum response factor-like protein 1). [swissprot;acc:q02078]		3738.82
1.06522	1086.73	482	pepsin a precursor (ec 3.4.23.1). [swissprot;acc:p00790]		1020.19
1.06564	898.833	349	kinesin-like protein kif13b (kinesin-like protein gakin). [swissprot;acc:q9nqt8]	High confidence	957.833
1.06618	1171	481	mitochondrial 39s ribosomal protein l39 (l39mt) (mrp-l39) (mrp-l5) (pred22 protein). [swissprot;acc:q9nyk5]	Low confidence	1248.5
1.0664	13463.1	348	baculoviral iap repeat-containing protein 5 (apoptosis inhibitor survivin) (apoptosis inhibitor 4). [swissprot;acc:o15392]	High confidence	14357.1
1.06693	1591.6	347	adenylate kinase isoenzyme 4, mitochondrial (ec 2.7.4.3) (atp-amp transphosphorylase). [swissprot;acc:p27144]		1491.75
1.06708	1721.76	346	3-ketoacyl-coa thiolase, peroxisomal precursor (ec 2.3.1.16) (beta- ketothiolase) (acetyl-coa acyltransferase) (peroxisomal 3-oxoacyl- coa thiolase). [swissprot;acc:p09110]		1837.26
1.0672	2255.28	345	collagen alpha 5(iv) chain precursor. [swissprot;acc:p29400]		2113.27
1.06775	2780.2	480	60s ribosomal protein l7a (surfeit locus protein 3) (pla-x polypeptide). [swissprot;acc:p11518]	Low confidence	2603.79
1.0679	3905.15	479	myocyte-specific enhancer factor 2c. [swissprot;acc:q06413]		3656.84
1.06825	2138.64	478	cleavage and polyadenylation specificity factor, 160 kda subunit (cpsf 160 kda subunit). [swissprot;acc:q10570]		2002
1.06837	1149.89	477	my016 protein. [sptrembl;acc:q9h3k6]		1228.51
1.06868	1439.32	476	pr-domain zinc finger protein 16 (transcription factor mel1). [swissprot;acc:q9haz2]		1346.82
1.06871	5556.34	475	early hematopoietic zinc finger. [refseq;acc:nm_015461]		5938.14
1.06988	2220.68	344	hydroxyindole o-methyltransferase (ec 2.1.1.4) (hiomt) (acetylserotonin o-methyltransferase) (asmt). [swissprot;acc:p46597]	High confidence	2075.64

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.