Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.


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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Gene Rank Network Comparison Type Value Type green Interaction Map description network_comparison red Filtered
Results: HTML CSV LaTeX Showing element 1901 to 1950 of 3228 in total
Network Comparison Type  : Divided
Value Type  : Ranked
Interaction Map  : High confidence
Filtered  : 1
Rank
green
description
network_comparison
red
1901 193.39 delta(14)-sterol reductase (ec 1.3.1.70) (c-14 sterol reductase) (sterol c14-reductase) (delta14-sr) (transmembrane 7 superfamily member 2) (another new gene 1) (putative sterol reductase sr-1). [swissprot;acc:o76062] 1.01034 191.411
1902 lamin b receptor (integral nuclear envelope inner membrane protein) (lmn2r). [swissprot;acc:q14739]
1903 193.385 solute carrier family 27 member 3; fatty acid transport protein 3. [refseq;acc:nm_024330] 191.406
1904 193.404 very-long-chain acyl-coa synthetase (ec 6.2.1.-) (very-long-chain- fatty-acid-coa ligase). [swissprot;acc:o14975] 191.424
1905 193.39 disrupter of silencing 10. [refseq;acc:nm_020368] 191.411
1906 193.389 very long-chain acyl-coa synthetase homolog 1. [refseq;acc:nm_014031] 191.41
1907 193.387 solute carrier family 27 (fatty acid transporter), member 5; very long-chain acyl-coa synthetase homolog 2; very long-chain acyl-coa synthetase-related protein; likely ortholog of mouse solute carrier family 27 (fatty acid transporter), member 5. [refseq;acc:nm_012254] 191.408
1908 193.394 similar to cg7020 gene product (fragment). [sptrembl;acc:q96ib4] 191.415
1909 215.256 calmegin precursor. [swissprot;acc:o14967] 1.01033 217.48
1910 calnexin precursor (major histocompatibility complex class i antigen-binding protein p88) (p90) (ip90). [swissprot;acc:p27824]
1911 soluble liver antigen/liver pancreas antigen. [refseq;acc:nm_153825]
1912 rna (guanine-7-) methyltransferase. [refseq;acc:nm_003799]
1913 213.564 phospholipid scramblase 3 (pl scramblase 3) (ca(2+)-dependent phospholipid scramblase 3). [swissprot;acc:q9nry6] 1.01021 215.745
1914 phospholipid scramblase 4 (pl scramblase 4) (ca(2+)-dependent phospholipid scramblase 4). [swissprot;acc:q9nrq2]
1915 213.571 phospholipid scramblase 2 (pl scramblase 2) (ca(2+)-dependent phospholipid scramblase 2). [swissprot;acc:q9nry7] 1.01019 215.747
1916 198.88 rh type c glycoprotein. [refseq;acc:nm_016321] 1.01016 196.88
1917 218.039 p28 ing5. [refseq;acc:nm_032329] 1.01015 215.848
1918 200.18 endothelial-derived gene 1. [refseq;acc:nm_025205] 202.211
1919 185.349 histidyl-trna synthetase homolog (ec 6.1.1.21) (histidine--trna ligase homolog) (hisrs). [swissprot;acc:p49590] 187.231
1920 185.413 histidyl-trna synthetase (ec 6.1.1.21) (histidine--trna ligase) (hisrs). [swissprot;acc:p12081] 1.01013 187.292
1921 219.386 5-methyltetrahydrofolate--homocysteine methyltransferase (ec 2.1.1.13) (methionine synthase, vitamin-b12 dependent) (ms). [swissprot;acc:q99707] 1.01012 221.607
1922 218.452 centaurin gamma 2. [swissprot;acc:q9upq3] 1.0101 220.659
1923 general vesicular transport factor p115 (transcytosis associated protein) (tap) (vesicle docking protein). [swissprot;acc:o60763]
1924 centaurin gamma 1. [swissprot;acc:q99490]
1925 centaurin gamma 3. [swissprot;acc:q96p47]
1926 198.91 rhesus blood group, b glycoprotein; rh type b glycoprotein. [refseq;acc:nm_020407] 1.01008 196.925
1927 198.914 rhesus blood group-associated glycoprotein (erythrocyte plasma membrane 50 kda glycoprotein) (rh50a). [swissprot;acc:q02094] 1.01006 196.932
1928 198.935 blood group rh(d) polypeptide (rhesus d antigen) (rhxiii) (rh polypeptide 2) (rhpii). [swissprot;acc:q02161] 1.01001 196.964
1929 217.574 enigma protein; lim domain protein. [refseq;acc:nm_005451] 219.753
1930 198.935 blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577] 196.964
1931 217.574 eukaryotic translation initiation factor 3 subunit 7 (eif-3 zeta) (eif3 p66) (eif3d). [swissprot;acc:o15371] 219.753
1932 198.936 blood group rh(ce) polypeptide (rhesus c/e antigens) (rh30a) (rhixb) (rh polypeptide 1) (rhpi). [swissprot;acc:p18577] 196.965
1933 217.82 ornithine carbamoyltransferase, mitochondrial precursor (ec 2.1.3.3) (otcase) (ornithine transcarbamylase). [swissprot;acc:p00480] 1.00998 215.667
1934 222.055 gamma adducin (adducin-like protein 70). [swissprot;acc:q9uey8] 1.00995 224.264
1935 216.279 abhydrolase domain containing protein 2 (protein phps1-2). [swissprot;acc:p08910] 218.43
1936 196.347 creatine kinase, sarcomeric mitochondrial precursor (ec 2.7.3.2) (s- mtck) (mib-ck) (basic-type mitochondrial creatine kinase). [swissprot;acc:p17540] 198.3
1937 216.279 quaking isoform 6. [sptrembl;acc:q9p0x9] 218.43
1938 196.341 creatine kinase, ubiquitous mitochondrial precursor (ec 2.7.3.2) (u- mtck) (mia-ck) (acidic-type mitochondrial creatine kinase). [swissprot;acc:p12532] 1.00994 198.293
1939 196.319 peptidyl prolyl isomerase h; cyclophilin h. [refseq;acc:nm_006347] 1.00988 198.258
1940 196.252 creatine kinase, b chain (ec 2.7.3.2) (b-ck). [swissprot;acc:p12277] 198.19
1941 196.319 prp18 pre-mrna processing factor 18 homolog. [refseq;acc:nm_003675] 198.258
1942 j domain protein c21orf55. [swissprot;acc:q9nx36] 1.00987 198.257
1943 222.147 megf11 protein. [refseq;acc:nm_032445] 224.34
1944 222.148 megf10 protein. [refseq;acc:nm_032446] 224.341
1945 222.151 beta adducin (erythrocyte adducin beta subunit). [swissprot;acc:p35612] 224.343
1946 212.142 nuclear factor, interleukin 3 regulated. [refseq;acc:nm_005384] 1.00986 214.234
1947 127.083 protein phosphatase inhibitor 2 (ipp-2). [swissprot;acc:p41236] 1.00984 125.845
1948 212.432 15 kda selenoprotein precursor. [swissprot;acc:o60613] 214.522
1949 216.663 rna-binding protein with multiple splicing (rbp-ms). [swissprot;acc:q93062] 218.794
1950 213.747 vacuolar protein sorting 18 (hvps18). [swissprot;acc:q9p253] 1.00982 215.847

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.
- http://analysis.yellowcouch.org/