MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Value Type	Network Comparison Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 151 to 200 of 7460 in total

Value Type  : Ranked
Interaction Map  : High confidence

description	Rank	Network Comparison Type	Filtered	red	green	network_comparison
40s ribosomal protein s16. [swissprot;acc:p17008]	326	Subtracted	1	241.828	263.62	21.792
	391	Divided				1.09011
40s ribosomal protein s18 (ke-3) (ke3). [swissprot;acc:p25232]	324	Subtracted		242.238	264.11	21.872
	387	Divided				1.09029
40s ribosomal protein s19. [swissprot;acc:p39019]	820	Subtracted		234.025	224.958	9.067
	861	Divided				1.04031
40s ribosomal protein s2 (s4) (llrep3 protein). [swissprot;acc:p15880]	176	Subtracted	0	11935.1	10592.8	1342.3
	186	Divided				1.12672
	269	Subtracted	1	241.625	265.136	23.511
	344	Divided				1.0973
40s ribosomal protein s20. [swissprot;acc:p17075]	251	Subtracted		243.5	267.21	23.71
	342	Divided				1.09737
40s ribosomal protein s21. [swissprot;acc:p35265]	756	Subtracted		224.244	234.511	10.267
	790	Divided				1.04578
40s ribosomal protein s23. [swissprot;acc:p39028]	234	Subtracted		243.944	268.195	24.251
	324	Divided				1.09941
40s ribosomal protein s24 (s19). [swissprot;acc:p16632]	1657	Subtracted		224.091	227.184	3.093
	1690	Divided				1.0138
40s ribosomal protein s26. [swissprot;acc:p02383]	68	Subtracted	0	14269.7	17098	2828.3
	112	Divided				1.1982
	440	Subtracted	1	210.224	226.578	16.354
	454	Divided				1.07779
40s ribosomal protein s27 (metallopan-stimulin 1) (mps-1). [swissprot;acc:p42677]	380		0	9566.15	9936.37	1.0387
	395	Subtracted				370.22
	1034		1	229.442	235.974	6.532
	1102	Divided				1.02847
40s ribosomal protein s28. [swissprot;acc:p25112]	195	Subtracted	0	12967.1	14193.6	1226.5
	258	Divided				1.09459
	1982		1	200.343	198.427	1.00966
	2000	Subtracted				1.916
40s ribosomal protein s29. [swissprot;acc:p30054]	198			241.849	267.642	25.793
	225	Divided	0	11035.3	9997.71	1.10378
	235	Subtracted				1037.59
	277	Divided	1	241.849	267.642	1.10665
40s ribosomal protein s3. [swissprot;acc:p23396]	270	Subtracted		241.612	265.119	23.507
	346	Divided				1.09729
40s ribosomal protein s30. [swissprot;acc:q05472]	1025	Subtracted		223.44	216.875	6.565
	1081	Divided				1.03027
40s ribosomal protein s3a. [swissprot;acc:p49241]	331		0	10405.1	10992.4	1.05644
	343	Subtracted				587.3
	825		1	225.689	234.674	8.985
	867	Divided				1.03981
40s ribosomal protein s4, x isoform (single copy abundant mrna protein) (scr10). [swissprot;acc:p12750]	203	Subtracted		240.758	266.078	25.32
	232		0	12448.9	11393.9	1055
	261	Divided				1.09259
	288		1	240.758	266.078	1.10517
40s ribosomal protein s4, y isoform 2. [swissprot;acc:q8td47]	202	Subtracted			266.079	25.321
	231		0	12447.6	11392.6	1055
	260	Divided				1.0926
	287		1	240.758	266.079	1.10517

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.