MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Rank	Gene	Value Type	Network Comparison Type	green	Interaction Map	Filtered	red	network_comparison

Results: HTML CSV LaTeX

Showing element 51 to 100 of 8289 in total

Value Type  : Ranked
Network Comparison Type  : Divided
Filtered  : 1

description	Rank	green	Interaction Map	red	network_comparison
26s protease regulatory subunit 4 (p26s4). [swissprot;acc:q03527]	2962	196.692	Low confidence	200.017	1.0169
26s protease regulatory subunit 6a (tat-binding protein 1) (tbp-1) (proteasome subunit p50). [swissprot;acc:p17980]	2474	217.285	High confidence	216.64	1.00298
	2595	196.948	Low confidence	200.484	1.01795
26s protease regulatory subunit 6b (mip224) (mb67 interacting protein) (tat-binding protein-7) (tbp-7). [swissprot;acc:p43686]	1991	195.763		199.582	1.01951
	2327	218.426	High confidence	217.413	1.00466
26s protease regulatory subunit 7 (mss1 protein). [swissprot;acc:p35998]	2321	194.732	Low confidence	198.366	1.01866
	2395	219.014	High confidence	218.192	1.00377
26s protease regulatory subunit 8 (proteasome subunit p45) (thyroid hormone receptor interacting protein 1) (trip1) (msug1 protein) (tat-binding protein homolog 10) (tbp10) (p45/sug). [swissprot;acc:p47210]	1637	199.408		202.358	1.01479
	2163	197.22	Low confidence	200.982	1.01908
26s protease regulatory subunit s10b (proteasome subunit p42) (p44) (conserved atpase domain protein 44) (cadp44). [swissprot;acc:q92524]	2478	216.801	High confidence	216.177	1.00289
	3515	197.374	Low confidence	200.312	1.01489
26s proteasome non-atpase regulatory subunit 1 (26s proteasome regulatory subunit s1) (26s proteasome subunit p112). [swissprot;acc:q99460]	857	199.229		204.36	1.02575
	2368	219.434	High confidence	218.555	1.00402
26s proteasome non-atpase regulatory subunit 10 (26s proteasome regulatory subunit p28) (gankyrin). [swissprot;acc:o75832]	2269	218.627		217.419	1.00556
	3038	197.031	Low confidence	200.303	1.01661
26s proteasome non-atpase regulatory subunit 11 (26s proteasome regulatory subunit s9) (26s proteasome regulatory subunit p44.5). [swissprot;acc:o00231]	2174	193.995		197.69	1.01905
	2367	218.475	High confidence	217.589	1.00407
26s proteasome non-atpase regulatory subunit 12 (26s proteasome regulatory subunit p55). [swissprot;acc:o00232]	2316	218.311		217.241	1.00493
	3393	195.526	Low confidence	198.522	1.01532
26s proteasome non-atpase regulatory subunit 13 (26s proteasome regulatory subunit s11) (26s proteasome regulatory subunit p40.5). [swissprot;acc:q9unm6]	2329	218.116	High confidence	217.112	1.00462
	2798	197.228	Low confidence	200.64	1.0173
26s proteasome non-atpase regulatory subunit 2 (26s proteasome regulatory subunit s2) (26s proteasome subunit p97) (tumor necrosis factor type 1 receptor associated protein 2) (55.11 protein). [swissprot;acc:q13200]	1918	195.527		199.382	1.01972
	2175	208.808	High confidence	210.209	1.00671
26s proteasome non-atpase regulatory subunit 3 (26s proteasome regulatory subunit s3) (proteasome subunit p58). [swissprot;acc:o43242]	2440	218.376		217.645	1.00336
	2613	196.947	Low confidence	200.463	1.01785
26s proteasome non-atpase regulatory subunit 4 (26s proteasome regulatory subunit s5a) (rpn10) (multiubiquitin chain binding protein) (antisecretory factor-1) (af) (asf). [swissprot;acc:p55036]	1432	225.468	High confidence	220.987	1.02028
	2995	196.383	Low confidence	199.67	1.01674
26s proteasome non-atpase regulatory subunit 6 (26s proteasome regulatory subunit s10) (p42a) (proteasome regulatory particle subunit p44s10). [swissprot;acc:q15008]	1832	196.175		200.092	1.01997
	2432	216.556	High confidence	215.807	1.00347
26s proteasome non-atpase regulatory subunit 7 (26s proteasome regulatory subunit s12) (proteasome subunit p40) (mov34 protein homolog). [swissprot;acc:p51665]	2355	218.162		217.232	1.00428
	3198	197.129	Low confidence	200.29	1.01604
26s proteasome non-atpase regulatory subunit 8 (26s proteasome regulatory subunit s14) (p31). [swissprot;acc:p48556]	1798	196.088		200.037	1.02014
	2525	216.341	High confidence	215.835	1.00234
26s proteasome non-atpase regulatory subunit 9 (26s proteasome regulatory subunit p27). [swissprot;acc:o00233]	2077	196.58	Low confidence	200.371	1.01928
	2620	215.91	High confidence	215.615	1.00137
26s proteasome-associated pad1 homolog. [refseq;acc:nm_005805]	2150	219.366		217.871	1.00686
	2964	197.26	Low confidence	200.589	1.01688
27 kda golgi snare protein (golgi snap receptor complex member 2) (membrin). [swissprot;acc:o14653]	70	235.017		259.517	1.10425
	810	221.785	High confidence	212.386	1.04425
28s ribosomal protein s12, mitochondrial precursor (mpr-s12) (mt- rps12). [swissprot;acc:o15235]	325	268.195		243.944	1.09941
	4510	210.759	Low confidence	208.988	1.00847
28s ribosomal protein s16, mitochondrial precursor (mrp-s16) (cgi- 132). [swissprot;acc:q9y3d3]	729	200.165		205.65	1.0274
	2212	225.854	High confidence	224.411	1.00643
28s ribosomal protein s17, mitochondrial precursor (mrp-s17) (hspc011). [swissprot;acc:q9y2r5]	9	44	Low confidence	58	1.31818
	23		High confidence
28s ribosomal protein s18a, mitochondrial precursor (mrp-s18-a) (mrps18a) (mrp-s18-3). [swissprot;acc:q9nvs2]	1659	214.826		217.925	1.01443
	2664	197.699	Low confidence	201.194	1.01768
28s ribosomal protein s18b, mitochondrial precursor (mrp-s18-b) (mrps18b) (mrp-s18-2) (ptd017 protein) (hspc183). [swissprot;acc:q9y676]	3958	204.37		201.908	1.01219
28s ribosomal protein s18c, mitochondrial precursor (mrp-s18-c) (mrps18c) (mrp-s18-1) (cgi-134). [swissprot;acc:q9y3d5]	3329	197.742		200.825	1.01559
28s ribosomal protein s26, mitochondrial precursor (mrp-s26) (mrp- s13). [swissprot;acc:q9byn8]	730	201.05		206.555	1.02738

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.