MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

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description	green	Filtered	red	network_comparison	Value Type	Interaction Map	Gene	Rank	Network Comparison Type

Results: HTML CSV LaTeX

Showing element 601 to 650 of 2121 in total

green  : 0
Filtered  : 1
red  : 0
network_comparison  : 0
Interaction Map  : High confidence
Network Comparison Type  : Subtracted

description	Value Type	Rank
gamma-interferon inducible lysosomal thiol reductase precursor (gamma-interferon-inducible protein ip-30). [swissprot;acc:p13284]	Ranked	3101
	Squared
	Rooted
gdp-fucose protein o-fucosyltransferase 1 precursor (ec 2.4.1.221) (peptide o-fucosyltransferase) (o-fuct-1). [swissprot;acc:q9h488]	Measured	3125
	Ranked
	Squared
	Rooted
geranylgeranyl transferase type ii beta subunit (ec 2.5.1.-) (rab geranylgeranyltransferase beta subunit) (rab geranyl- geranyltransferase beta subunit) (rab gg transferase beta) (rab ggtase beta). [swissprot;acc:p53611]	Measured	2963
	Ranked
	Squared
	Rooted
glioma pathogenesis-related protein (glipr) (rtvp-1 protein). [swissprot;acc:p48060]	Measured	2953
	Ranked
	Squared
	Rooted
glioma tumor suppressor candidate region gene 2 protein (p60). [swissprot;acc:q9nzm5]	Measured	3104
	Ranked
	Squared
	Rooted
glioma-amplified sequence-41; numa binding protein 1. [refseq;acc:nm_006530]	Measured	3007
	Ranked
	Squared
	Rooted
glucosamine-6-phosphate isomerase (ec 3.5.99.6) (glucosamine-6- phosphate deaminase) (gnpda) (glcn6p deaminase) (oscillin). [swissprot;acc:p46926]	Measured	3058
	Ranked
	Squared
	Rooted
glucosamine-6-phosphate isomerase. [refseq;acc:nm_138335]	Measured	2861
	Ranked
	Squared
	Rooted
glutamyl aminopeptidase (ec 3.4.11.7) (eap) (aminopeptidase a) (apa) (differentiation antigen gp160). [swissprot;acc:q07075]	Measured	2957
	Ranked
	Squared
	Rooted
glycerol-3-phosphate acyltransferase, mitochondrial precursor (ec 2.3.1.15) (gpat). [swissprot;acc:q9hcl2]	Measured	3033
	Ranked
	Squared
	Rooted
glycine receptor alpha-1 chain precursor (glycine receptor 48 kda subunit) (strychnine binding subunit). [swissprot;acc:p23415]	Measured	2919
	Ranked
	Squared
	Rooted
glycine receptor alpha-2 chain precursor. [swissprot;acc:p23416]	Measured	3121
	Ranked
	Squared
	Rooted
glycine receptor alpha-3 chain precursor. [swissprot;acc:o75311]	Measured	2920
	Ranked
	Squared

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.