MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

MK5 Proteome Analysis

Table 3: Type II network, divided ranks. This table presents the output of the simulation of a type-II network in which we relied on the high confidence interactions and micro-array results. The output of the micro-array was then ranked and these ranks used as input into the network simulation. After performing two such simulations (one for the MK5 off and one for the MK5 on microarray output), we divided the ranks and sorted the results accordingly. The output of this technique is a collection of proteins that cluster naturally together.

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Rank	description	Network Comparison Type	Gene	Hugo	Value Type	Interaction Map	Filtered	red	green	network_comparison

Results: HTML CSV LaTeX

Showing element 1075 to 1124 of 2060 in total

Network Comparison Type  : Subtracted
Interaction Map  : High confidence
Filtered  : 1
red  : 0
green  : 0
network_comparison  : 0

Rank	description	Hugo	Value Type
3024	phosphatidylinositol glycan class t precursor. [refseq;acc:nm_015937]	PIGT	Squared
			Rooted
3025	dj579f20.1 (high-mobility group (nonhistone chromosomal) protein 1-like 1). [sptrembl;acc:q9nqj4]	HMG1L1	Measured
			Ranked
			Squared
			Rooted
3026	solute carrier family 36 member 1; proton / amino acid symporter; lysosomal amino acid transporter 1. [refseq;acc:nm_078483]	SLC36A1	Measured
			Ranked
			Squared
			Rooted
3027	elongation factor ts, mitochondrial precursor (ef-ts) (ef-tsmt). [swissprot;acc:p43897]	TSFM	Measured
			Ranked
			Squared
			Rooted
3028	clll6 protein. [refseq;acc:nm_020456]	C13orf1	Measured
			Ranked
			Squared
			Rooted
3029	dynein intermediate chain 1, axonemal (axonemal dynein intermediate chain 1). [swissprot;acc:q9ui46]	DNAI1	Measured
			Ranked
			Squared
			Rooted
3030	uncharacterized bone marrow protein bm033. [refseq;acc:nm_018452]	C6orf35	Measured
			Ranked
			Squared
			Rooted
3031	speckle-type poz protein. [swissprot;acc:o43791]	SPOP	Measured
			Ranked
			Squared
			Rooted
3032	similar to lysozyme c-1 (1,4-beta-n-acylmuramidase c, ec 3.2.1.17). [refseq;acc:nm_032517]	LYZL1	Measured
			Ranked
			Squared
			Rooted
3033	glycerol-3-phosphate acyltransferase, mitochondrial precursor (ec 2.3.1.15) (gpat). [swissprot;acc:q9hcl2]	GPAM	Measured
			Ranked
			Squared
			Rooted
3034	postsynaptic protein cript; hspc139 protein. [refseq;acc:nm_014171]	CRIPT	Measured
			Ranked
			Squared
			Rooted
3035	transforming growth factor beta 3 precursor (tgf-beta 3). [swissprot;acc:p10600]	TGFB3	Measured
			Ranked
			Squared
			Rooted
3036	placenta growth factor precursor (plgf). [swissprot;acc:p49763]	PGF	Measured
			Ranked
			Squared
			Rooted

Legend:
- Rank is the rank after comparing the two networks
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Hugo is the HGNC identifier if it exists
- Value Type describes how the microarray measurement was processed. Ranked indicates that we sorted all measurements and use the rank as red and green value. Measured is the normal measurement. Squared and Rooted are the square and square root respecitcely. This might be valueable to compensate for non linear light distributions.
- Network Comparison Type describes whether we divided the red and green types or whether we sutractcted them
- Interaction Map specifies whether we used only the hig hconfidence protein-protein interactions or also included the low confidence interactions.
- Filtered specifies whether we only included the high confidence microarry measurements or not.