MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	Ratio	description	Class	Accession	Gene Ontology	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 451 to 500 of 2667 in total

Regulation  : down

Ratio	description	Class	Gene Ontology
1.41851	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5). [Uniprot/SWISSPROT;Acc:Q9P104]	molecular function	transmembrane receptor protein tyrosine kinase signaling protein activity
1.42215	Sodium-dependent serotonin transporter (5HT transporter) (5HTT). [Uniprot/SWISSPROT;Acc:P31645]	biological process	monoamine transport
			neurotransmitter transport
			neurotransmitter uptake
			serotonin transport
		cellular component	integral to plasma membrane
			membrane
		molecular function	monoamine transporter activity
			neurotransmitter:sodium symporter activity
			protein binding
			serotonin transporter activity
			serotonin:sodium symporter activity
			symporter activity
1.43088	Isopentenyl-diphosphate Delta-isomerase 2 (EC 5.3.3.2) (IPP isomerase 2) (Isopentenyl pyrophosphate isomerase 2) (IPPI2). [Uniprot/SWISSPROT;Acc:Q9BXS1]	biological process	carotenoid biosynthetic process
			cholesterol biosynthetic process
			isoprenoid biosynthetic process
		cellular component	peroxisome
		molecular function	hydrolase activity
			isomerase activity
			isopentenyl-diphosphate delta-isomerase activity
			magnesium ion binding
1.43351	Carboxypeptidase A2 precursor (EC 3.4.17.15). [Uniprot/SWISSPROT;Acc:P48052]	biological process	proteolysis
			vacuolar protein catabolic process
		molecular function	carboxypeptidase A activity
			carboxypeptidase activity
			metal ion binding
			metallopeptidase activity
			zinc ion binding
1.44004	Cytokine-like protein 1 precursor (Protein C17). [Uniprot/SWISSPROT;Acc:Q9NRR1]	biological process	signal transduction
		cellular component	extracellular space
			soluble fraction
		molecular function	receptor binding
1.48363	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase) (WEE1hu). [Uniprot/SWISSPROT;Acc:P30291]	biological process	cell cycle
			cell division
			mitosis
			protein amino acid phosphorylation
			regulation of progression through cell cycle
		cellular component	nucleus
		molecular function	ATP binding
			magnesium ion binding
			nucleotide binding
			protein binding
			protein kinase activity
			protein serine/threonine kinase activity
			protein-tyrosine kinase activity
			transferase activity
1.48389	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin). [Uniprot/SWISSPROT;Acc:P49790]	biological process	ATP synthesis coupled proton transport
			intracellular protein transport across a membrane
			mRNA transport
			protein transport

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.