MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 850 to 899 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen). [Uniprot/SWISSPROT;Acc:P22607]	1.30142	down	forebrain development	biological process
			hair cell differentiation
			identical protein binding	molecular function
			inner ear development	biological process
			integral to membrane	cellular component
			integral to plasma membrane
			interleukin-1 receptor activity	molecular function
			internal side of plasma membrane	cellular component
			JAK-STAT cascade	biological process
			lysosome	cellular component
			MAPKKK cascade	biological process
			membrane	cellular component
			morphogenesis of an epithelium	biological process
			negative regulation of epithelial cell proliferation
			nucleotide binding	molecular function
			perinuclear region of cytoplasm	cellular component
			positive regulation of apoptosis	biological process
			positive regulation of cell differentiation
			positive regulation of peptidyl-tyrosine phosphorylation
			positive regulation of protein ubiquitination
			protein amino acid phosphorylation
			protein kinase activity	molecular function
			protein serine/threonine kinase activity
			protein-tyrosine kinase activity
			receptor activity
			sensory perception of sound	biological process
			skeletal development
			transferase activity	molecular function
Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3). [Uniprot/SWISSPROT;Acc:Q8TAT2]	1.18263	up	growth factor binding
Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein). [Uniprot/SWISSPROT;Acc:O15409]	1.57088		caudate nucleus development	biological process
			intracellular	cellular component
			metal ion binding	molecular function
			nucleic acid binding
			nucleus	cellular component
			protein homodimerization activity	molecular function
			putamen development	biological process
			regulation of transcription, DNA-dependent
			sequence-specific DNA binding	molecular function
			transcription	biological process
			transcription factor activity	molecular function
			zinc ion binding
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1) (Early estrogen-regulated protein). [Uniprot/SWISSPROT;Acc:Q9H0R8]	1.33817	down	autophagic vacuole	cellular component
			autophagic vacuole formation	biological process
			beta-tubulin binding	molecular function
			cytoplasm	cellular component
			GABA receptor binding	molecular function
			intracellular	cellular component
			microtubule
			protein binding	molecular function
GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein). [Uniprot/SWISSPROT;Acc:Q99501]	1.10233	up	cell cycle arrest	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.