Scientific
MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis
These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.
Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation description Class Gene Ontology Gene Minimum Ratio Accession Maximum Ratio
Results: HTML CSV LaTeX
Showing element 601 to 650 of 2667 in total

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\begin{longtable}{|c|c|c|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Regulation\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
description\vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
Class\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
Gene Ontology\vspace{3pt}}\\
\hline
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.25808\vspace{3pt}}&\multirow{10}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\parbox{\wcC}{\vspace{3pt}\noindent
Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). \vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
nucleotide binding\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{9}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.2734\vspace{3pt}}}&&\multirow{9}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Neurexin-2-alpha precursor (Neurexin II-alpha). \vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell adhesion\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
neurotransmitter secretion\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
synaptic transmission\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
synaptogenesis\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
membrane\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
calcium channel regulator activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
calcium ion binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\hline
\multirow{11}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.27461\vspace{3pt}}}&\multirow{11}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{11}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Homeobox protein Hox-D3 (Hox-4A). \vspace{3pt}}}&\multirow{5}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
anatomical structure morphogenesis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
G-protein coupled receptor protein signaling pathway\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
multicellular organismal development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of transcription, DNA-dependent\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
thyroid gland development\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
integral to membrane\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{4-5}
&&&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
DNA binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
galanin receptor activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
sequence-specific DNA binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
transcription factor activity\vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.27516\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}&\parbox{\wcC}{\vspace{3pt}\noindent
Uncharacterized protein C16orf48. \vspace{3pt}}&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
microtubule cytoskeleton\vspace{3pt}}\\\hline
\multirow{12}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.27696\vspace{3pt}}}&\multirow{16}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{12}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). \vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cell cycle\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
G1/S transition of mitotic cell cycle\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
multicellular organismal development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of cell proliferation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of cyclin-dependent protein kinase activity\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein amino acid dephosphorylation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
regulation of progression through cell cycle\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
response to DNA damage stimulus\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
nucleus\vspace{3pt}}\\\cline{4-5}
&&&\multirow{3}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein kinase binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein phosphatase type 1 activity\vspace{3pt}}\\\cline{1-1}\cline{3-5}
\multirow{4}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.27802\vspace{3pt}}}&&\multirow{4}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Melanoma-associated antigen B2 (MAGE-B2 antigen) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2). \vspace{3pt}}}&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
homoiothermy\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
response to freezing\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
ice binding\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\hline
\multirow{8}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.28319\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
up\vspace{3pt}}}&\multirow{8}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
Autophagy-related protein 10 (APG10-like). \vspace{3pt}}}&\multirow{5}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
autophagy\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
positive regulation of protein modification\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein amino acid lipidation\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
protein transport\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
ubiquitin cycle\vspace{3pt}}\\\cline{4-5}
&&&\multirow{2}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
cellular component\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cytoplasm\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
intracellular\vspace{3pt}}\\\cline{4-5}
&&&\parbox{\wcD}{\vspace{3pt}\noindent
molecular function\vspace{3pt}}&\parbox{\wcE}{\vspace{3pt}\noindent
protein binding\vspace{3pt}}\\\hline
\multirow{4}{*}{\parbox{\wcA}{\vspace{3pt}\noindent
1.28356\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcB}{\vspace{3pt}\noindent
down\vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcC}{\vspace{3pt}\noindent
T-box transcription factor TBX2 (T-box protein 2). \vspace{3pt}}}&\multirow{4}{*}{\parbox{\wcD}{\vspace{3pt}\noindent
biological process\vspace{3pt}}}&\parbox{\wcE}{\vspace{3pt}\noindent
cardiac muscle development\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
cell aging\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
heart morphogenesis\vspace{3pt}}\\\cline{5-5}
&&&&\parbox{\wcE}{\vspace{3pt}\noindent
homoiothermy\vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- http://analysis.yellowcouch.org/