Scientific

MK5 Microarray Data


Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 23 of 23 in total
Class	molecular function
Gene Ontology nucleic acid binding
Ratio Regulation description 1.07618 up U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20). [Source:Uniprot/SWISSPROT;Acc:Q15696] 1.1243 down Zinc finger protein basonuclin-2. [Source:Uniprot/SWISSPROT;Acc:Q6ZN30] 1.13007 up Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4] 1.16173 up oligonucleotide/oligosaccharide-binding fold containing 2B [Source:RefSeq_peptide;Acc:NP_076973] 1.19134 down Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4). [Source:Uniprot/SWISSPROT;Acc:P29122] 1.25113 down Zinc finger protein OZF (Only zinc finger protein) (Zinc finger protein 146). [Source:Uniprot/SWISSPROT;Acc:Q15072] 1.25808 up Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1] 1.42264 up RNA-binding protein 4 (RNA-binding motif protein 4) (RNA-binding motif protein 4a) (Lark homolog) (hLark). [Source:Uniprot/SWISSPROT;Acc:Q9BWF3] 1.57088 up Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein). [Source:Uniprot/SWISSPROT;Acc:O15409] 1.59188 up Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Source:Uniprot/SWISSPROT;Acc:Q8TF68] 1.60746 down Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein). [Source:Uniprot/SWISSPROT;Acc:Q8TD26] 1.66123 up KRAB-A domain containing 1 (KRBA1), mRNA [Source:RefSeq_dna;Acc:NM_032534] 1.66679 up TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7). [Source:Uniprot/SWISSPROT;Acc:Q7Z3E1] 1.78439 up Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta). [Source:Uniprot/SWISSPROT;Acc:Q14839] 1.81557 down Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80). [Source:Uniprot/SWISSPROT;Acc:Q9ULG1] 1.86204 down Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Source:Uniprot/SWISSPROT;Acc:Q8NAM6] 1.89168 down Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Source:Uniprot/SWISSPROT;Acc:O95125] 1.93995 up Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Source:Uniprot/SWISSPROT;Acc:Q92785] 2.45875 up ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19). [Source:Uniprot/SWISSPROT;Acc:Q8TE59] 2.86965 up RNA-binding protein 28 (RNA-binding motif protein 28). [Source:Uniprot/SWISSPROT;Acc:Q9NW13] 4.14054 up Protein odd-skipped-related 2. [Source:Uniprot/SWISSPROT;Acc:Q8N2R0] 4.87049 up zinc finger, FYVE domain containing 26 [Source:RefSeq_peptide;Acc:NP_056161] 5.83544 down Nucleoplasmin-2. [Source:Uniprot/SWISSPROT;Acc:Q86SE8] Legend: - The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration. - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. - The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/