Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation Ratio description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1 to 17 of 17 in total

Regulation: down
Class: biological process
Gene Ontology: signal transduction

\def\wcA{0.33333333333333\textwidth}
\def\wcB{0.33333333333333\textwidth}
\begin{longtable}{|c|c|}
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
Ratio\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
description\vspace{3pt}}\\
\hline
\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.1611\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Guanylin precursor (Guanylate cyclase activator 2A) (Guanylate cyclase-activating protein 1) (Gap-I) [Contains: HMW-guanylin; Guanylin]. \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.18821\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Cytokine receptor common beta chain precursor (GM-CSF/IL-3/IL-5 receptor common beta-chain) (CD131 antigen) (CDw131). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.19212\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Thyroglobulin precursor. \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.23783\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.24114\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Myosin-15 (Myosin heavy chain 15). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.36911\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.44004\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Cytokine-like protein 1 precursor (Protein C17). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.49923\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.5415\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.61347\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Calmodulin-like protein 5 (Calmodulin-like skin protein). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.80858\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Rhophilin-1 (GTP-Rho-binding protein 1). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
1.98137\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
2.44552\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Guanine nucleotide-binding protein alpha-14 subunit (G-protein alpha subunit 14). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
2.93895\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
3.27919\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Calsenilin (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
3.52215\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Olfactory receptor 4L1 (Olfactory receptor OR14-28). \vspace{3pt}}\\\hline
\parbox{\wcA}{\vspace{3pt}\noindent
3.54799\vspace{3pt}}&\parbox{\wcB}{\vspace{3pt}\noindent
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta 2 (Transducin beta chain 2) (G protein beta 2 subunit). \vspace{3pt}}\\\hline
nd{longtable}

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.

 - The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 

 - The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 

 - The Gene Ontology terms as linked to the specific gene.

 - Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray

 - Accession is the GO accession key. 

 - Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

 - Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/