MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	description	Ratio	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 2619 to 2667 of 2667 in total

Regulation  : up

description	Ratio	Class	Gene Ontology
Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage- gated calcium channel gamma-7 subunit). [Uniprot/SWISSPROT;Acc:P62955]	3.41415	molecular function	calcium ion binding
			voltage-gated calcium channel activity
			voltage-gated ion channel activity
Zinc finger protein 219. [Uniprot/SWISSPROT;Acc:Q9P2Y4]	1.13007	biological process	anion transport
			G-protein coupled receptor protein signaling pathway
			regulation of transcription, DNA-dependent
		cellular component	integral to membrane
			intracellular
			membrane
			nucleus
		molecular function	histamine receptor activity
			inorganic anion exchanger activity
			metal ion binding
			nucleic acid binding
			transcription factor activity
			zinc ion binding
Zinc finger protein 384 (Nuclear matrix transcription factor 4) (Nuclear matrix protein 4) (CAG repeat protein 1) (CAS-interacting zinc finger protein) (Trinucleotide repeat-containing gene 1 protein). [Uniprot/SWISSPROT;Acc:Q8TF68]	1.59188	biological process	regulation of transcription, DNA-dependent
			transcription
		cellular component	intracellular
			nucleus
		molecular function	DNA binding
			metal ion binding
			nucleic acid binding
			zinc ion binding
Zinc finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2). [Uniprot/SWISSPROT;Acc:Q92785]	1.93995	biological process	apoptosis
			induction of apoptosis by extracellular signals
			regulation of transcription, DNA-dependent
			transcription
		cellular component	cytoplasm
			intracellular
			nucleus
		molecular function	metal ion binding
			nucleic acid binding
			protein binding
			zinc ion binding
Zinc finger SWIM domain-containing protein 3. [Uniprot/SWISSPROT;Acc:Q96MP5]	1.56335		metal ion binding
			zinc ion binding
zinc finger, FYVE domain containing 26 [RefSeq_peptide;Acc:NP_056161]	4.87049	cellular component	intracellular
		molecular function	metal ion binding
			nucleic acid binding
			zinc ion binding
zinc transporter like 2 [RefSeq_peptide;Acc:NP_598003]	2.45764	biological process	cation transport
			zinc ion transport
		cellular component	cytoplasmic membrane-bound vesicle
			Golgi apparatus
			membrane
		molecular function	cation transporter activity
			protein binding
			zinc ion transporter activity

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.