MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	description	Ratio	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 151 to 200 of 2667 in total

Regulation  : down

description	Ratio	Class	Gene Ontology
Bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A). [Uniprot/SWISSPROT;Acc:P12643]	1.49558	biological process	negative regulation of cell proliferation
			negative regulation of progression through cell cycle
			odontogenesis (sensu Vertebrata)
			organ morphogenesis
			osteoblast differentiation
			positive regulation of astrocyte differentiation
			positive regulation of ossification
			positive regulation of osteoblast differentiation
			regulation of transcription
			ureteric bud branching
		cellular component	extracellular region
			extracellular space
		molecular function	cytokine activity
			growth factor activity
			protein binding
			transforming growth factor beta receptor binding
Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2). [Uniprot/SWISSPROT;Acc:Q86UW7]	1.24359	biological process	exocytosis
			protein transport
		cellular component	cell junction
			cytoplasmic vesicle
			membrane
			synapse
		molecular function	calcium ion binding
			lipid binding
Calcyphosin-2 (Calcyphosine-2). [Uniprot/SWISSPROT;Acc:Q9BXY5]	1.29424	biological process	ciliary or flagellar motility
		cellular component	flagellin-based flagellum
		molecular function	calcium ion binding
Calmodulin-like protein 5 (Calmodulin-like skin protein). [Uniprot/SWISSPROT;Acc:Q9NZT1]	1.61347	biological process	ciliary or flagellar motility
			epidermis development
			signal transduction
		cellular component	flagellin-based flagellum
		molecular function	calcium ion binding
			protein binding
Calsenilin (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM). [Uniprot/SWISSPROT;Acc:Q9Y2W7]	3.27919	biological process	apoptosis
			behavior
			ion transport
			negative regulation of transcription from RNA polymerase II promoter
			potassium ion transport
			regulation of neuron apoptosis
			regulation of transcription from RNA polymerase II promoter
			response to pain
			sensory perception of pain
			signal transduction
			transcription
		cellular component	cytoplasm
			cytosol
			endoplasmic reticulum
			Golgi apparatus
			membrane
			nucleus

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.