MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Gene Ontology	Gene	Regulation	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1093 to 1142 of 2667 in total

description	Ratio	Gene Ontology	Regulation	Class
Junctophilin-1 (Junctophilin type 1) (JP-1). [Uniprot/SWISSPROT;Acc:Q9HDC5]	3.39764	biological_process	down	biological process
		integral to membrane		cellular component
		junctional membrane complex
		membrane
		microsome
		molecular_function		molecular function
		muscle development		biological process
		sarcoplasmic reticulum		cellular component
		structural constituent of muscle		molecular function
		Z disc		cellular component
Kelch-like protein 34. [Uniprot/SWISSPROT;Acc:Q8N239]	1.21698	electron transport	up	biological process
		metabolic process
		oxidoreductase activity		molecular function
		protein binding
Keratin-associated protein 19-2. [Uniprot/SWISSPROT;Acc:Q3LHN2]	1.69153	intermediate filament	down	cellular component
Ketosamine-3-kinase (EC 2.7.1.-) (Fructosamine-3-kinase-related protein). [Uniprot/SWISSPROT;Acc:Q9HA64]	1.18141	kinase activity		molecular function
		transferase activity
KRAB-A domain containing 1 (KRBA1), mRNA [RefSeq_dna;Acc:NM_032534]	1.66123	G-protein coupled receptor protein signaling pathway	up	biological process
		intracellular		cellular component
		membrane
		muscarinic acetylcholine receptor activity		molecular function
		nucleic acid binding
		regulation of transcription, DNA-dependent		biological process
Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor). [Uniprot/SWISSPROT;Acc:Q96MU8]	3.89584	cell communication
		integral to membrane		cellular component
		membrane
		membrane fraction
		molecular_function		molecular function
		Wnt receptor signaling pathway		biological process
LAG1 longevity assurance homolog 4. [Uniprot/SWISSPROT;Acc:Q9HA82]	1.50206	ceramide biosynthetic process
		endoplasmic reticulum		cellular component
		integral to membrane
		lipid biosynthetic process		biological process
		membrane		cellular component
		nucleus
		regulation of transcription, DNA-dependent		biological process
		sequence-specific DNA binding		molecular function
		transcription factor activity
Lariat debranching enzyme (EC 3.1.-.-). [Uniprot/SWISSPROT;Acc:Q9UK59]	1.37411	hydrolase activity
		hydrolase activity, acting on ester bonds
		metal ion binding
		mRNA processing		biological process
		nuclear mRNA splicing, via spliceosome
		nucleus		cellular component
		RNA lariat debranching enzyme activity		molecular function
		RNA splicing, via transesterification reactions		biological process
leucine-rich repeat neuronal 6A [RefSeq_peptide;Acc:NP_116197]	2.79087	defense response	down
		integral to membrane		cellular component
		membrane
		protein binding		molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.