MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Ratio	description	Regulation	Gene Ontology	Class	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 850 to 899 of 2667 in total

Ratio	description	Regulation	Gene Ontology	Class
1.33465	T-box transcription factor TBX5 (T-box protein 5). [Uniprot/SWISSPROT;Acc:Q99593]	up	lung development	biological process
			morphogenesis of an epithelium
			multicellular organismal development
			negative regulation of cardiac muscle cell proliferation
			negative regulation of cell migration
			nucleus	cellular component
			pattern specification process	biological process
			pericardium development
			positive regulation of cardioblast differentiation
			positive regulation of transcription from RNA polymerase II promoter
			positive regulation of transcription, DNA-dependent
			protein binding	molecular function
			regulation of transcription, DNA-dependent	biological process
			RNA polymerase II transcription factor activity	molecular function
			sequence-specific DNA binding
			transcription	biological process
			transcription factor activity	molecular function
			transcriptional activator activity
1.33817	Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1) (Early estrogen-regulated protein). [Uniprot/SWISSPROT;Acc:Q9H0R8]	down	autophagic vacuole	cellular component
			autophagic vacuole formation	biological process
			beta-tubulin binding	molecular function
			cytoplasm	cellular component
			GABA receptor binding	molecular function
			intracellular	cellular component
			microtubule
			protein binding	molecular function
1.34001	Protein DmX-like 2 (Rabconnectin-3). [Uniprot/SWISSPROT;Acc:Q8TDJ6]	up	cell junction	cellular component
			cytoplasmic vesicle
			membrane
			Rab GTPase binding	molecular function
			synapse	cellular component
			synaptic vesicle
1.34491	Bardet-Biedl syndrome 5 protein. [Uniprot/SWISSPROT;Acc:Q8N3I7]		cellular_component
			cilium
			intracellular
			molecular_function	molecular function
			response to stimulus	biological process
			visual perception
1.34969	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (Cdc25C- associated protein kinase 1) (cTAK1) (C-TAK1) (Serine/threonine protein kinase p78) (Ser/Thr protein kinase PAR-1) (Protein kinase STK10). [Uniprot/SWISSPROT;Acc:P27448]		ATP binding	molecular function
			nucleotide binding
			protein amino acid phosphorylation	biological process
			protein binding	molecular function
			protein kinase activity
			protein serine/threonine kinase activity
			protein-tyrosine kinase activity
			transferase activity
1.35022	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)]. [Uniprot/SWISSPROT;Acc:O15527]		base-excision repair	biological process
			cellular_component	cellular component
			damaged DNA binding	molecular function
			DNA binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.