Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes


Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].
Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio
Results: HTML CSV LaTeX Showing element 1 to 28 of 28 in total 
Class	molecular function
Gene Ontology	transcription factor activity

Ratio	Regulation	description	
1.10889	up	Nuclear receptor-binding factor 2 (NRBF-2) (Comodulator of PPAR and RXR). [Source:Uniprot/SWISSPROT;Acc:Q96F24]	
1.13007	up	Zinc finger protein 219. [Source:Uniprot/SWISSPROT;Acc:Q9P2Y4]	
1.16921	up	Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1). [Source:Uniprot/SWISSPROT;Acc:Q96HZ4]	
1.22576	up	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1). [Source:Uniprot/SWISSPROT;Acc:Q9UIS9]	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Source:Uniprot/SWISSPROT;Acc:Q13207]	
1.30407	up	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H). [Source:Uniprot/SWISSPROT;Acc:O15522]	
1.31661	up	Chloride anion exchanger (Protein DRA) (Down-regulated in adenoma) (Solute carrier family 26 member 3). [Source:Uniprot/SWISSPROT;Acc:P40879]	
1.33465	up	T-box transcription factor TBX5 (T-box protein 5). [Source:Uniprot/SWISSPROT;Acc:Q99593]	
1.45624	up	Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2). [Source:Uniprot/SWISSPROT;Acc:Q16621]	
1.50206	up	LAG1 longevity assurance homolog 4. [Source:Uniprot/SWISSPROT;Acc:Q9HA82]	
1.57088	up	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein). [Source:Uniprot/SWISSPROT;Acc:O15409]	
1.69345	up	GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9). [Source:Uniprot/SWISSPROT;Acc:P16383]	
1.86204	down	Zinc finger and SCAN domain-containing protein 4 (Zinc finger protein 494). [Source:Uniprot/SWISSPROT;Acc:Q8NAM6]	
1.89168	down	Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10). [Source:Uniprot/SWISSPROT;Acc:O95125]	
1.98137	down	Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). [Source:Uniprot/SWISSPROT;Acc:P35398]	
2.10428	up	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39). [Source:Uniprot/SWISSPROT;Acc:P05412]	
2.58329	down	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L). [Source:Uniprot/SWISSPROT;Acc:Q9UL68]	
2.86298	up	T-brain-1 protein (T-box brain protein 1) (TBR-1) (TES-56). [Source:Uniprot/SWISSPROT;Acc:Q16650]	
3.29064	down	Transcription factor GATA-6 (GATA-binding factor 6). [Source:Uniprot/SWISSPROT;Acc:Q92908]	
3.48313	down	Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGFB-induced factor 2) (TGF(beta)-induced transcription factor 2). [Source:Uniprot/SWISSPROT;Acc:Q9GZN2]	
3.70292	up	Homeobox protein SIX4 (Sine oculis homeobox homolog 4). [Source:Uniprot/SWISSPROT;Acc:Q9UIU6]	
3.81736	up	Transcription factor E2F3 (E2F-3). [Source:Uniprot/SWISSPROT;Acc:O00716]	
3.83977	down	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac). [Source:Uniprot/SWISSPROT;Acc:Q8WYP5]	
4.04651	up	Sad1/unc-84-like protein 2 (Rab5-interacting protein) (Rab5IP). [Source:Uniprot/SWISSPROT;Acc:Q9UH99]	
4.4149	down	X box-binding protein 1 (XBP-1) (Tax-responsive element-binding protein 5). [Source:Uniprot/SWISSPROT;Acc:P17861]	
4.55177	up	Transcription factor SOX-14. [Source:Uniprot/SWISSPROT;Acc:O95416]	
5.32612	down	Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (T cell transcription factor NFAT4) (NF-AT4) (NFATx). [Source:Uniprot/SWISSPROT;Acc:Q12968]	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.
- http://analysis.yellowcouch.org/