MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Regulation	Ratio	description	Gene Ontology	Accession	Class	Gene	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 1551 to 1600 of 2667 in total

Regulation  : up

Ratio	description	Gene Ontology	Class
1.29151	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (hOrbit2). [Uniprot/SWISSPROT;Acc:O75122]	binding	molecular function
		cell cycle	biological process
		cell division
		cytoplasm	cellular component
		cytoplasmic microtubule
		cytoskeleton
		establishment and/or maintenance of cell polarity	biological process
		galactoside 2-alpha-L-fucosyltransferase activity	molecular function
		Golgi apparatus	cellular component
		kinetochore microtubule
		microtubule binding	molecular function
		microtubule plus-end binding
		mitosis	biological process
		negative regulation of microtubule depolymerization
		protein binding	molecular function
		regulation of microtubule polymerization or depolymerization	biological process
1.29238	Coiled-coil and C2 domain-containing protein 1B. [Uniprot/SWISSPROT;Acc:Q5T0F9]	FAD binding	molecular function
		oxidoreductase activity
1.30407	Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H). [Uniprot/SWISSPROT;Acc:O15522]	axonogenesis	biological process
		multicellular organismal development
		nucleus	cellular component
		regulation of transcription, DNA-dependent	biological process
		RNA polymerase II transcription factor activity	molecular function
		sequence-specific DNA binding
		transcription factor activity
		transcription from RNA polymerase II promoter	biological process
1.31661	Chloride anion exchanger (Protein DRA) (Down-regulated in adenoma) (Solute carrier family 26 member 3). [Uniprot/SWISSPROT;Acc:P40879]	anion exchanger activity	molecular function
		anion transport	biological process
		antiporter activity	molecular function
		apical plasma membrane	cellular component
		brush border membrane
		chloride ion binding	molecular function
		cytochrome complex assembly	biological process
		excretion
		heme transport
		heme transporter activity	molecular function
		integral to membrane	cellular component
		membrane
		membrane fraction
		sulfate porter activity	molecular function
		sulfate transport	biological process
		transcription cofactor activity	molecular function
		transcription factor activity
		transport	biological process
		transporter activity	molecular function
1.31895	Fc receptor-like 1 [RefSeq_peptide;Acc:NP_443170]	receptor activity
1.33329	Beta-mannosidase precursor (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase). [Uniprot/SWISSPROT;Acc:O00462]	beta-mannosidase activity
		carbohydrate metabolic process	biological process
		cation binding	molecular function
		glycoprotein catabolic process	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.