MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description	Ratio	Regulation	Gene Ontology	Class	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 901 to 950 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein). [Uniprot/SWISSPROT;Acc:Q99501]	1.10233	up	cytoskeleton	cellular component
GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9). [Uniprot/SWISSPROT;Acc:P16383]	1.69345		DNA binding	molecular function
			nucleus	cellular component
			regulation of transcription	biological process
			regulation of transcription, DNA-dependent
			RNA polymerase II transcription factor activity	molecular function
			transcription factor activity
Geminin. [Uniprot/SWISSPROT;Acc:O75496]	1.35125		cell cycle	biological process
			negative regulation of DNA replication
			negative regulation of progression through cell cycle
			nucleus	cellular component
			organ morphogenesis	biological process
			protein binding	molecular function
			regulation of progression through cell cycle	biological process
Glutathione peroxidase 6 precursor (EC 1.11.1.9). [Uniprot/SWISSPROT;Acc:P59796]	3.74971		glutathione peroxidase activity	molecular function
			oxidoreductase activity
			response to oxidative stress	biological process
			selenium binding	molecular function
Glycerophosphodiester phosphodiesterase domain-containing protein 2 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 3) (Osteoblast differentiation promoting factor). [Uniprot/SWISSPROT;Acc:Q9HCC8]	1.37801		cytoplasm	cellular component
			cytoskeleton
			glycerol metabolic process	biological process
			glycerophosphodiester phosphodiesterase activity	molecular function
			hydrolase activity
			integral to membrane	cellular component
			membrane
			metabolic process	biological process
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2). [Uniprot/SWISSPROT;Acc:Q8WTR4]	3.54928	down	cytoplasm	cellular component
			glycerol metabolic process	biological process
			glycerophosphodiester phosphodiesterase activity	molecular function
			hydrolase activity
			integral to membrane	cellular component
			membrane
GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1). [Uniprot/SWISSPROT;Acc:P36959]	4.40598	up	catalytic activity	molecular function
			GMP reductase activity
			metabolic process	biological process
			metal ion binding	molecular function
			nucleotide metabolic process	biological process
			oxidoreductase activity	molecular function
			potassium ion binding
			response to cold	biological process
Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372). [Uniprot/SWISSPROT;Acc:Q14789]	1.45148		DNA binding	molecular function
			ER-Golgi intermediate compartment	cellular component
			Golgi apparatus
			Golgi membrane
			Golgi organization and biogenesis	biological process
			Golgi stack	cellular component
			integral to membrane
			membrane
			nucleus
			protein binding	molecular function

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.