MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 900 to 949 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
GAS2-like protein 1 (Growth arrest-specific 2-like 1) (GAS2-related protein on chromosome 22) (GAR22 protein). [Uniprot/SWISSPROT;Acc:Q99501]	1.10233	up	cellular component	cytoplasm
				cytoskeleton
GC-rich sequence DNA-binding factor (GCF) (Transcription factor 9) (TCF-9). [Uniprot/SWISSPROT;Acc:P16383]	1.69345		biological process	regulation of transcription
				regulation of transcription, DNA-dependent
			cellular component	nucleus
			molecular function	DNA binding
				RNA polymerase II transcription factor activity
				transcription factor activity
Geminin. [Uniprot/SWISSPROT;Acc:O75496]	1.35125		biological process	cell cycle
				negative regulation of DNA replication
				negative regulation of progression through cell cycle
				organ morphogenesis
				regulation of progression through cell cycle
			cellular component	nucleus
			molecular function	protein binding
Glutathione peroxidase 6 precursor (EC 1.11.1.9). [Uniprot/SWISSPROT;Acc:P59796]	3.74971		biological process	response to oxidative stress
			molecular function	glutathione peroxidase activity
				oxidoreductase activity
				selenium binding
Glycerophosphodiester phosphodiesterase domain-containing protein 2 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 3) (Osteoblast differentiation promoting factor). [Uniprot/SWISSPROT;Acc:Q9HCC8]	1.37801		biological process	glycerol metabolic process
				metabolic process
			cellular component	cytoplasm
				cytoskeleton
				integral to membrane
				membrane
			molecular function	glycerophosphodiester phosphodiesterase activity
				hydrolase activity
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 2). [Uniprot/SWISSPROT;Acc:Q8WTR4]	3.54928	down	biological process	glycerol metabolic process
			cellular component	cytoplasm
				integral to membrane
				membrane
			molecular function	glycerophosphodiester phosphodiesterase activity
				hydrolase activity
GMP reductase 1 (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1). [Uniprot/SWISSPROT;Acc:P36959]	4.40598	up	biological process	metabolic process
				nucleotide metabolic process
				response to cold
			molecular function	catalytic activity
				GMP reductase activity
				metal ion binding
				oxidoreductase activity
				potassium ion binding
Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372). [Uniprot/SWISSPROT;Acc:Q14789]	1.45148		biological process	Golgi organization and biogenesis
				regulation of transcription, DNA-dependent
				vesicle-mediated transport
			cellular component	ER-Golgi intermediate compartment
				Golgi apparatus
				Golgi membrane
				Golgi stack
				integral to membrane
				membrane

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.