MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

Navigation/Query Panel:
Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

Regulation	Ratio	description	Class	Gene Ontology	Gene	Minimum Ratio	Maximum Ratio	Accession

Results: HTML CSV LaTeX

Showing element 851 to 900 of 2667 in total

Regulation  : down

Ratio	description	Class	Gene Ontology
2.58329	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L). [Uniprot/SWISSPROT;Acc:Q9UL68]	molecular function	calcium ion binding
			metal ion binding
			transcription factor activity
			zinc ion binding
2.61135	28S ribosomal protein S35, mitochondrial precursor (S35mt) (MRP-S35) (Mitochondrial ribosomal protein S28) (MRP-S28). [Uniprot/SWISSPROT;Acc:P82673]	biological process	DNA damage response, detection of DNA damage
			peptide biosynthetic process
		cellular component	mitochondrial small ribosomal subunit
			mitochondrion
			ribonucleoprotein complex
2.75593	ubiquilin-like [RefSeq_peptide;Acc:NP_659490]	biological process	protein modification process
2.79087	leucine-rich repeat neuronal 6A [RefSeq_peptide;Acc:NP_116197]		defense response
		cellular component	integral to membrane
			membrane
		molecular function	protein binding
2.83611	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator). [Uniprot/SWISSPROT;Acc:Q9UJW9]	biological process	negative regulation of cell growth
			positive regulation of transcription
			regulation of transcription, DNA-dependent
			transcription
		cellular component	nucleus
		molecular function	protein binding
			transcriptional activator activity
2.85383	Uncharacterized protein C20orf142 precursor. [Uniprot/SWISSPROT;Acc:Q8N6M3]	cellular component	integral to membrane
			membrane
2.88128	CD302 antigen precursor (C-type lectin domain family 13 member A) (C- type lectin BIMLEC) (Type I transmembrane C-type lectin receptor DCL- 1). [Uniprot/SWISSPROT;Acc:Q8IX05]		integral to membrane
			membrane
		molecular function	sugar binding
2.88235	Anion exchange protein 3 (Neuronal band 3-like protein) (Solute carrier family 4 member 3) (Cardiac/brain band 3-like protein) (CAE3/BAE3). [Uniprot/SWISSPROT;Acc:P48751]	biological process	anion transport
		cellular component	integral to membrane
			integral to plasma membrane
			membrane
			membrane fraction
		molecular function	anion exchanger activity
			antiporter activity
			inorganic anion exchanger activity
2.93895	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF). [Uniprot/SWISSPROT;Acc:Q92844]	biological process	I-kappaB kinase/NF-kappaB cascade
			signal transduction
		cellular component	cytoplasm
		molecular function	metal ion binding
			protein binding
			zinc ion binding
3.00923	Arylamine N-acetyltransferase 1 (EC 2.3.1.5) (Arylamide acetylase 1) (Monomorphic arylamine N-acetyltransferase) (MNAT) (N- acetyltransferase type 1) (NAT-1). [Uniprot/SWISSPROT;Acc:P18440]	biological process	metabolic process
		cellular component	cytoplasm
		molecular function	acetyltransferase activity
			arylamine N-acetyltransferase activity
			transferase activity
3.05037	Thrombospondin-4 precursor. [Uniprot/SWISSPROT;Acc:P35443]	biological process	cell adhesion
			substrate-bound cell migration, cell extension
		cellular component	extracellular region
			proteinaceous extracellular matrix
		molecular function	calcium ion binding

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.