MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Gene Ontology	Gene	Class	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 800 to 849 of 2667 in total

description	Ratio	Regulation	Gene Ontology	Class
Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2) (Tyrosine-protein kinase TYRO6). [Uniprot/SWISSPROT;Acc:P54753]	3.48558	up	axon guidance	biological process
			axon guidance receptor activity	molecular function
			ephrin receptor activity
			integral to plasma membrane	cellular component
			membrane
			nucleotide binding	molecular function
			protein amino acid phosphorylation	biological process
			protein kinase activity	molecular function
			protein serine/threonine kinase activity
			protein-tyrosine kinase activity
			receptor activity
			signal transduction	biological process
			transferase activity	molecular function
			transmembrane receptor protein tyrosine kinase signaling pathway	biological process
Epididymal-specific lipocalin-12 precursor. [Uniprot/SWISSPROT;Acc:Q6JVE5]	2.51088	down	binding	molecular function
			lipid metabolic process	biological process
			structural constituent of cell wall	molecular function
			transport	biological process
			transporter activity	molecular function
eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [RefSeq_dna;Acc:NM_001099408]	1.11519	up	cytoplasm	cellular component
			RNA binding	molecular function
			translation initiation factor activity
			translational initiation	biological process
Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog). [Uniprot/SWISSPROT;Acc:Q9Y2L1]	1.683	down	cytoplasm	cellular component
			exonuclease activity	molecular function
			exosome (RNase complex)	cellular component
			GDP-dissociation stimulator activity	molecular function
			hydrolase activity
			nucleus	cellular component
			ribonuclease activity	molecular function
			RNA binding
			rRNA processing	biological process
F-box only protein 15. [Uniprot/SWISSPROT;Acc:Q8NCQ5]	2.33107		protein binding	molecular function
			SCF ubiquitin ligase complex	cellular component
			ubiquitin cycle	biological process
F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5). [Uniprot/SWISSPROT;Acc:Q969U6]	1.50715		protein binding	molecular function
			ubiquitin cycle	biological process
Fc receptor-like 1 [RefSeq_peptide;Acc:NP_443170]	1.31895	up	receptor activity	molecular function
Fibroblast growth factor 5 precursor (FGF-5) (HBGF-5) (Smag-82). [Uniprot/SWISSPROT;Acc:P12034]	1.82311	down	cell proliferation	biological process
			cell-cell signaling
			extracellular space	cellular component
			fibroblast growth factor receptor signaling pathway	biological process
			glial cell differentiation
			growth factor activity	molecular function
			nervous system development	biological process
			regulation of progression through cell cycle
Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen). [Uniprot/SWISSPROT;Acc:P22607]	1.30142		ATP binding	molecular function
			cell growth	biological process
			fibroblast growth factor receptor activity	molecular function
			fibroblast growth factor receptor signaling pathway	biological process

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.