MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Ratio	Regulation	Class	Gene Ontology	Gene	Accession	Minimum Ratio	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 790 to 839 of 2667 in total

description	Ratio	Regulation	Class	Gene Ontology
Enhancer of polycomb homolog 1. [Uniprot/SWISSPROT;Acc:Q9H2F5]	4.49282	down	biological process	regulation of transcription, DNA-dependent
				transcription
			cellular component	nuclear membrane
				nucleoplasm
				nucleus
			molecular function	transcriptional activator activity
				transcriptional repressor activity
Enoyl-CoA hydratase domain-containing protein 1. [Uniprot/SWISSPROT;Acc:Q9NTX5]	4.22898	up	biological process	metabolic process
			molecular function	catalytic activity
Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2) (Tyrosine-protein kinase TYRO6). [Uniprot/SWISSPROT;Acc:P54753]	3.48558		biological process	axon guidance
				protein amino acid phosphorylation
				signal transduction
				transmembrane receptor protein tyrosine kinase signaling pathway
			cellular component	integral to plasma membrane
				membrane
			molecular function	ATP binding
				axon guidance receptor activity
				ephrin receptor activity
				nucleotide binding
				protein kinase activity
				protein serine/threonine kinase activity
				protein-tyrosine kinase activity
				receptor activity
				transferase activity
Epididymal-specific lipocalin-12 precursor. [Uniprot/SWISSPROT;Acc:Q6JVE5]	2.51088	down	biological process	lipid metabolic process
				transport
			molecular function	binding
				structural constituent of cell wall
				transporter activity
eukaryotic translation initiation factor 4E family member 1B (EIF4E1B), mRNA [RefSeq_dna;Acc:NM_001099408]	1.11519	up	biological process	translational initiation
			cellular component	cytoplasm
			molecular function	RNA binding
				translation initiation factor activity
Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog). [Uniprot/SWISSPROT;Acc:Q9Y2L1]	1.683	down	biological process	rRNA processing
			cellular component	cytoplasm
				exosome (RNase complex)
				nucleus
			molecular function	exonuclease activity
				GDP-dissociation stimulator activity
				hydrolase activity
				ribonuclease activity
				RNA binding
F-box only protein 15. [Uniprot/SWISSPROT;Acc:Q8NCQ5]	2.33107		biological process	ubiquitin cycle
			cellular component	SCF ubiquitin ligase complex
			molecular function	protein binding
F-box/WD repeat protein 5 (F-box and WD-40 domain protein 5). [Uniprot/SWISSPROT;Acc:Q969U6]	1.50715		biological process	ubiquitin cycle
			molecular function	protein binding
Fc receptor-like 1 [RefSeq_peptide;Acc:NP_443170]	1.31895	up		receptor activity
Fibroblast growth factor 5 precursor (FGF-5) (HBGF-5) (Smag-82). [Uniprot/SWISSPROT;Acc:P12034]	1.82311	down	biological process	cell proliferation
				cell-cell signaling

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.