Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Click on the attribute name to hide/unhide it. The green arrows can be used to shift columns left/right. Exact word match is written as =..., regular expressions can be matched with ~.... To select all values larger or equal than use >.... This would be <... for values smaller or equal than. To select all values within a specific range use [...,...].

description Ratio Regulation Gene Ontology Class Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 601 to 650 of 688 in total

Class

: cellular component

description	Ratio	Regulation	Gene Ontology
TBK1 binding protein 1 [RefSeq_peptide;Acc:NP_055541]	1.351	down	integral to membrane
TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7). [Uniprot/SWISSPROT;Acc:Q7Z3E1]	1.66679	up	nucleus
Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8) (Tetraspanin TM4-A). [Uniprot/SWISSPROT;Acc:O60637]	3.07625	down	integral to membrane
	3.07625	down	membrane
THO complex subunit 2 (Tho2). [Uniprot/SWISSPROT;Acc:Q8NI27]	1.28698	up	nucleus
Threonyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.3) (Threonine--tRNA ligase) (ThrRS) (Threonyl-tRNA synthetase-like 1). [Uniprot/SWISSPROT;Acc:Q9BW92]	2.25955	down	cytoplasm
	2.25955		mitochondrion
Thrombospondin-4 precursor. [Uniprot/SWISSPROT;Acc:P35443]	3.05037		extracellular region
Thrombospondin-4 precursor. [Uniprot/SWISSPROT;Acc:P35443]	3.05037		proteinaceous extracellular matrix
Thyroglobulin precursor. [Uniprot/SWISSPROT;Acc:P01266]	1.19212		extracellular region
Toll-interacting protein. [Uniprot/SWISSPROT;Acc:Q9H0E2]	3.54414	up	cytoplasm
			interleukin-1 receptor complex
			interleukin-18 receptor complex
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF). [Uniprot/SWISSPROT;Acc:Q92844]	2.93895	down	cytoplasm
Transcription cofactor HES-6 (Hairy and enhancer of split 6) (C- HAIRY1). [Uniprot/SWISSPROT;Acc:Q96HZ4]	1.16921	up	nucleus
	1.16921		transcription factor complex
Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39). [Uniprot/SWISSPROT;Acc:P05412]	2.10428		nuclear chromosome
			nucleus
			transcription factor complex
Transcription factor E2F3 (E2F-3). [Uniprot/SWISSPROT;Acc:O00716]	3.81736		nucleus
	3.81736		transcription factor complex
Transcription factor GATA-6 (GATA-binding factor 6). [Uniprot/SWISSPROT;Acc:Q92908]	3.29064	down	nucleus
Transcription factor NF-E2 45 kDa subunit (Nuclear factor, erythroid- derived 2 45 kDa subunit) (p45 NF-E2) (Leucine zipper protein NF-E2). [Uniprot/SWISSPROT;Acc:Q16621]	1.45624	up	nucleus
Transcription factor SOX-14. [Uniprot/SWISSPROT;Acc:O95416]	4.55177		chromatin
Transcription factor SOX-14. [Uniprot/SWISSPROT;Acc:O95416]	4.55177		nucleus
Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC [Uniprot/SWISSPROT;Acc:Q9HBA0]	1.60668		integral to membrane
			membrane
			plasma membrane
transient receptor potential cation channel, subfamily C, member 2 (TRPC2) on chromosome 11 [RefSeq_dna;Acc:NR_002720]	1.16158		membrane
transient receptor potential cation channel, subfamily M, member 1 [RefSeq_peptide;Acc:NP_002411]	2.8521		integral to plasma membrane
			membrane
			membrane fraction
Transmembrane emp24 domain-containing protein 1 precursor (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor- binding protein). [Uniprot/SWISSPROT;Acc:Q13445]	1.14915		integral to membrane
	1.14915		membrane
Transmembrane protein 116. [Uniprot/SWISSPROT;Acc:Q8NCL8]	1.82063	down	integral to membrane
Transmembrane protein 116. [Uniprot/SWISSPROT;Acc:Q8NCL8]	1.82063	down	membrane
Transmembrane protein 181. [Uniprot/SWISSPROT;Acc:Q9P2C4]	3.14866	up	integral to membrane
Transmembrane protein 181. [Uniprot/SWISSPROT;Acc:Q9P2C4]	3.14866	up	membrane
Tripartite motif-containing protein 58 (Protein BIA2). [Uniprot/SWISSPROT;Acc:Q8NG06]	1.31489	down	intracellular
Tubulin-specific chaperone E (Tubulin-folding cofactor E). [Uniprot/SWISSPROT;Acc:Q15813]	5.84607		cytoplasm
			cytoskeleton
			microtubule
Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14). [Uniprot/SWISSPROT;Acc:Q9H3S7]	1.62709	up	cytoplasmic vesicle
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit- related protein 2 (U2(RNU2) small nuclear RNA auxiliary factor 1-like 2) (CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2) (Renal carcinoma antigen NY-REN-20). [Uniprot/SWISSPROT;Acc:Q15696]	1.07618		integral to membrane
			nucleus
			ribonucleoprotein complex
			U12-dependent spliceosome
Ubiquitin-activating enzyme E1 domain-containing protein 1 (UFM1- activating enzyme) (Ubiquitin-activating enzyme 5) (ThiFP1). [Uniprot/SWISSPROT;Acc:Q9GZZ9]	8.21788		cytoplasm
	8.21788		nucleus
Ubiquitin-conjugating enzyme E2 Q2 (EC 6.3.2.19) (Ubiquitin-protein ligase Q2) (Ubiquitin carrier protein Q2). [Uniprot/SWISSPROT;Acc:Q8WVN8]	1.59763	down	cytoplasm

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.

- http://analysis.yellowcouch.org/