MK5 Microarray Data

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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description	Class	Ratio	Gene Ontology	Regulation	Gene	Minimum Ratio	Accession	Maximum Ratio

Results: HTML CSV LaTeX

Showing element 601 to 650 of 2667 in total

description	Class	Ratio	Gene Ontology	Regulation
COX16-like protein C14orf112, mitochondrial precursor. [Uniprot/SWISSPROT;Acc:Q9P0S2]	cellular component	1.40451	integral to membrane	down
			membrane
			mitochondrion
Cullin-4B (CUL-4B). [Uniprot/SWISSPROT;Acc:Q13620]	biological process	1.49271	cell cycle
			DNA repair
			ubiquitin cycle
	cellular component		cellular_component
	molecular function		molecular_function
			protein binding
Cyclin-A2 (Cyclin-A). [Uniprot/SWISSPROT;Acc:P20248]	biological process	1.45635	cell cycle	up
			cell division
			mitosis
			mitotic G2 checkpoint
			positive regulation of transcription
			regulation of cyclin-dependent protein kinase activity
			regulation of progression through cell cycle
	cellular component		cytoplasm
			female pronucleus
			male pronucleus
			nucleus
	molecular function		protein binding
Cyclin-I. [Uniprot/SWISSPROT;Acc:Q14094]	biological process	1.36349	regulation of progression through cell cycle	down
			spermatogenesis
Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7). [Uniprot/SWISSPROT;Acc:Q9Y697]		1.19539	amino acid metabolic process	up
			metabolic process
			protein complex assembly
			sulfur amino acid metabolic process
	cellular component		cytoplasm
			cytosol
			mitochondrion
			nucleus
	molecular function		catalytic activity
			cysteine desulfurase activity
			lyase activity
			pyridoxal phosphate binding
			transaminase activity
			transferase activity
Cysteine-rich hydrophobic domain 2 protein (BrX-like translocated in leukemia). [Uniprot/SWISSPROT;Acc:Q9UKJ5]	biological process	1.63639	biological_process
	cellular component		cellular_component
			cytoplasmic vesicle
			Golgi apparatus
			Golgi-associated vesicle
			plasma membrane
	molecular function		molecular_function
Cystinosin. [Uniprot/SWISSPROT;Acc:O60931]	biological process	1.75846	amino acid metabolic process	down
			L-cystine transport
			transport
	cellular component		integral to membrane
			lysosomal membrane
			lysosome

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells.
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component.
- The Gene Ontology terms as linked to the specific gene.
- Gene is the ensembl human gene identifier measured by 1 or more probes on the microarray
- Accession is the GO accession key.
- Minimum Ratio is the lowest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.
- Maximum Ratio is the highest expected regulation ratio based on the replicate slides and a 95% symmetric confidence interval.