Scientific

MK5 Microarray Data

Affected Genes - Ontology Breakdown - Gene Enrichment - Proteome Analysis

These are the micro-array results of a differential gene expression microarray experiments and the subsequent analysis steps performed on them. The up/down- regulation ratio was obtained by measuring WT cells against MK5 activated cells. See material and methods for technical information as well as the data usage policy.

Affected Genes

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Ratio Regulation description Class Gene Ontology Gene Accession Minimum Ratio Maximum Ratio

Results: HTML CSV LaTeX

Showing element 601 to 650 of 2667 in total

Ratio	Regulation	description	Class	Gene Ontology	
1.25808	up	Chromodomain-helicase-DNA-binding protein 7 (EC 3.6.1.-) (ATP- dependent helicase CHD7) (CHD-7). [Source:Uniprot/SWISSPROT;Acc:Q9P2D1]	molecular function	nucleotide binding	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	biological process	cell adhesion	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	biological process	neurotransmitter secretion	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	biological process	synaptic transmission	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	biological process	synaptogenesis	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	cellular component	integral to membrane	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	cellular component	membrane	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	molecular function	calcium channel regulator activity	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	molecular function	calcium ion binding	
1.2734	up	Neurexin-2-alpha precursor (Neurexin II-alpha). [Source:Uniprot/SWISSPROT;Acc:Q9P2S2]	molecular function	protein binding	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	biological process	anatomical structure morphogenesis	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	biological process	G-protein coupled receptor protein signaling pathway	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	biological process	multicellular organismal development	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	biological process	regulation of transcription, DNA-dependent	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	biological process	thyroid gland development	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	cellular component	integral to membrane	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	cellular component	nucleus	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	molecular function	DNA binding	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	molecular function	galanin receptor activity	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	molecular function	sequence-specific DNA binding	
1.27461	down	Homeobox protein Hox-D3 (Hox-4A). [Source:Uniprot/SWISSPROT;Acc:P31249]	molecular function	transcription factor activity	
1.27516	up	Uncharacterized protein C16orf48. [Source:Uniprot/SWISSPROT;Acc:Q9H0I2]	cellular component	microtubule cytoskeleton	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	cell cycle	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	G1/S transition of mitotic cell cycle	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	multicellular organismal development	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	positive regulation of cell proliferation	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	positive regulation of cyclin-dependent protein kinase activity	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	protein amino acid dephosphorylation	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	regulation of progression through cell cycle	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	biological process	response to DNA damage stimulus	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	cellular component	nucleus	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	molecular function	protein binding	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	molecular function	protein kinase binding	
1.27696	down	Speedy protein A (Speedy-1) (Spy1) (Rapid inducer of G2/M progression in oocytes A) (RINGO A) (hSpy/Ringo A). [Source:Uniprot/SWISSPROT;Acc:Q5MJ70]	molecular function	protein phosphatase type 1 activity	
1.27802	down	Melanoma-associated antigen B2 (MAGE-B2 antigen) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2). [Source:Uniprot/SWISSPROT;Acc:O15479]	biological process	homoiothermy	
1.27802	down	Melanoma-associated antigen B2 (MAGE-B2 antigen) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2). [Source:Uniprot/SWISSPROT;Acc:O15479]	biological process	response to freezing	
1.27802	down	Melanoma-associated antigen B2 (MAGE-B2 antigen) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2). [Source:Uniprot/SWISSPROT;Acc:O15479]	molecular function	ice binding	
1.27802	down	Melanoma-associated antigen B2 (MAGE-B2 antigen) (DSS-AHC critical interval MAGE superfamily 6) (DAM6) (MAGE XP-2). [Source:Uniprot/SWISSPROT;Acc:O15479]	molecular function	protein binding	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	biological process	autophagy	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	biological process	positive regulation of protein modification	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	biological process	protein amino acid lipidation	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	biological process	protein transport	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	biological process	ubiquitin cycle	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	cellular component	cytoplasm	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	cellular component	intracellular	
1.28319	up	Autophagy-related protein 10 (APG10-like). [Source:Uniprot/SWISSPROT;Acc:Q9H0Y0]	molecular function	protein binding	
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Source:Uniprot/SWISSPROT;Acc:Q13207]	biological process	cardiac muscle development	
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Source:Uniprot/SWISSPROT;Acc:Q13207]	biological process	cell aging	
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Source:Uniprot/SWISSPROT;Acc:Q13207]	biological process	heart morphogenesis	
1.28356	down	T-box transcription factor TBX2 (T-box protein 2). [Source:Uniprot/SWISSPROT;Acc:Q13207]	biological process	homoiothermy	

Legend:
- The Ratio specifies how much this gene is up/down regulated. When up- or down-regulated must this value respectively be multiplied/divided to obtain the MK5 on concentration based on the MK5 off concentration.
- The Regulation specifies how this gene is affected when going from the MK5 off cells to the MK5 on cells. 
- The Class refers to the ontology category, which can be molecular_function, biological_process or cellular_component. 
- The Gene Ontology terms as linked to the specific gene.

- http://analysis.yellowcouch.org/